Åke Borg
Principal investigator
MAD for Cancer research:
Publications
Displaying of publications. Sorted by year, then title.
BRCA1 frameshift variants leading to extended incorrect protein C termini
Thales C. Nepomuceno, Tzeh Keong Foo, Marcy E. Richardson, John Michael O. Ranola, Jamie Weyandt, et al.
(2023) Human Genetics and Genomics Advances, 4
Journal articleMatched analysis of circulating selenium with the breast cancer selenotranscriptome: a multicentre prospective study
Kamil Demircan, Ylva Bengtsson, Thilo Samson Chillon, Johan Vallon-Christersson, Qian Sun, et al.
(2023) Journal of Translational Medicine
Journal articleExtended genetic analysis and tumor characteristics in over 4600 women with suspected hereditary breast and ovarian cancer
Anna Öfverholm, Therese Törngren, Anna Rosén, Brita Arver, Zakaria Einbeigi, et al.
(2023) BMC Cancer, 23 p.1-12
Journal articleSerum copper, zinc and copper/zinc ratio in relation to survival after breast cancer diagnosis: A prospective multicenter cohort study
Ylva Bengtsson, Kamil Demircan, Johan Vallon-Christersson, Martin Malmberg, Lao Saal, et al.
(2023) Redox Biology, 63
Journal articleMolecular characteristics of breast tumors in patients screened for germline predisposition from a population-based observational study
Deborah F. Nacer, Johan Vallon-Christersson, Nicklas Nordborg, Hans Ehrencrona, Anders Kvist, et al.
(2023) Genome Medicine, 15 p.1-20
Journal articleValidation of the BOADICEA model for predicting the likelihood of carrying pathogenic variants in eight breast and ovarian cancer susceptibility genes
Nanna Bæk Møller, Desirée Sofie Boonen, Elisabeth Simone Feldner, Qin Hao, Martin Larsen, et al.
(2023) Scientific Reports, 13
Journal articleOvarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2
D.G. O’Mahony, A. Borg, Wendy K Chung
(2023) British Journal of Cancer, 128 p.2283-2294
Journal articleObesity-associated changes in molecular biology of primary breast cancer
H.-L. Nguyen, A. Borg, C. Desmedt
(2023) Nature Communications, 14
Journal articleClinical, splicing, and functional analysis to classify BRCA2 exon 3 variants : Application of a points-based ACMG/AMP approach
Mads Thomassen, Romy L.S. Mesman, Thomas V.O. Hansen, Mireia Menendez, Maria Rossing, et al.
(2022) Human Mutation, 43 p.1921-1944
Journal articleMerged testing for colorectal cancer syndromes and re-evaluation of genetic variants improve diagnostic yield : Results from a nationwide prospective cohort
Sara Svensson, Theofanis Zagoras, Christos Aravidis, Marie Stenmark Askmalm, Erik Björck, et al.
(2022) Genes Chromosomes and Cancer, 61 p.585-591
Journal articleHow Reliable Are Gene Expression-Based and Immunohistochemical Biomarkers Assessed on a Core-Needle Biopsy? A Study of Paired Core-Needle Biopsies and Surgical Specimens in Early Breast Cancer
Hani Saghir, Srinivas Veerla, Martin Malmberg, Lisa Rydén, Anna Ehinger, et al.
(2022) Cancers, 14 p.1-16
Journal articleRNA sequencing-based single sample predictors of molecular subtype and risk of recurrence for clinical assessment of early-stage breast cancer
Johan Staaf, Jari Häkkinen, Cecilia Hegardt, Lao H Saal, Siker Kimbung, et al.
(2022) npj Breast Cancer, 8 p.1-17
Journal articleAutoimmunity to selenoprotein P predicts breast cancer recurrence
Kamil Demircan, Qian Sun, Ylva Bengtsson, Petra Seemann, Johan Vallon-Christersson, et al.
(2022) Redox Biology, 53
Journal articleCancer Risks Associated With BRCA1 and BRCA2 Pathogenic Variants
S. Li, Å. Borg, A.C. Antoniou
(2022) Journal of Clinical Oncology, 40 p.1529-1541
Journal articleRNA sequencing-based single sample predictors of molecular subtype and risk of recurrence for clinical assessment of early-stage breast cancer
J. Vallon-Christersson, J. Staaf, J. Häkkinen, C. Hegardt, L. Saal, et al.
(2022) Annals of Oncology, 33 p.144-145
Conference paper: abstractInterval breast cancer is associated with interferon immune response
Emilio Ugalde-Morales, Felix Grassmann, Keith Humphreys, Jingmei Li, Mikael Eriksson, et al.
(2022) European Journal of Cancer, 162 p.194-205
Journal articleRisks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants
H. Li, Åke Borg, David E. Goldgar
(2022) Genetics in Medicine, 24 p.119-129
Journal articleBreast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores
D.R. Barnes, A. Borg, L. Ottini
(2022) Journal of the National Cancer Institute, 114 p.109-122
Journal articleSample preparation approach influences pam50 risk of recurrence score in early breast cancer
Tonje G. Lien, Hege Oma Ohnstad, Ole Christian Lingjærde, Johan Vallon-Christersson, Marit Aaserud, et al.
(2021) Cancers, 13
Journal articlePrecision oncology of high-grade ovarian cancer defined through targeted sequencing
Sandra Wessman, Beatriz Bohorquez Fuentes, Therese Törngren, Anders Kvist, Georgia Kokaraki, et al.
(2021) Cancers, 13
Journal articleA search for modifying genetic factors in CHEK2:c.1100delC breast cancer patients
Camilla Wendt, Taru A Muranen, Lotta Mielikäinen, Jessada Thutkawkorapin, Carl Blomqvist, et al.
(2021) Scientific Reports, 11 p.1-9
Journal articleCDKN2A genetic testing in melanoma-prone families in Sweden in the years 2015-2020 : implications for novel national recommendations
Maria Pissa, Teo Helkkula, Frida Appelqvist, Gustav Silander, Åke Borg, et al.
(2021) Acta oncologica (Stockholm, Sweden), 60 p.888-896
Journal articlePreexisting Somatic Mutations of Estrogen Receptor Alpha (ESR1) in Early-Stage Primary Breast Cancer
Malin Dahlgren, Anthony George, Christian Brueffer, Sergii Gladchuk, Yilun Chen, et al.
(2021) JNCI Cancer Spectrum, 5
Journal articleDistinct mechanisms of resistance to fulvestrant treatment dictate level of ER independence and selective response to CDK inhibitors in metastatic breast cancer
Kamila Kaminska, Nina Akrap, Johan Staaf, Carla L Alves, Anna Ehinger, et al.
(2021) Breast cancer research : BCR, 23 p.26-26
Journal articleAssociation between breast cancer risk and disease aggressiveness : Characterizing underlying gene expression patterns
Emilio Ugalde-Morales, Felix Grassmann, Keith Humphreys, Jingmei Li, Mikael Eriksson, et al.
(2021) International Journal of Cancer, 148 p.884-894
Journal articleMolecular analyses of triple-negative breast cancer in the young and elderly
Mattias Aine, Ceren Boyaci, Johan Hartman, Jari Häkkinen, Shamik Mitra, et al.
(2021) Breast cancer research : BCR, 23
Journal articleA case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers
Juliette Coignard, Annelie Augustinsson, Håkan Olsson, Åke Borg, Antonis C Antoniou
(2021) Nature Communications, 12
Journal articleSerum selenium, selenoprotein P and glutathione peroxidase 3 as predictors of mortality and recurrence following breast cancer diagnosis: A multicentre cohort study
Kamil Demircan, Ylva Bengtsson, Qian Sun, Annie Brange, Johan Vallon-Christersson, et al.
(2021) Redox Biology, 47 p.1-12
Journal articleBreast cancer risk genes - Association analysis in more than 113,000 women
Leila Dorling, Jeanette Valcich, Minerva Li, Therese Törngren, Åke Borg, et al.
(2021) New England Journal of Medicine, 384 p.428-439
Journal articleThe spatial RNA integrity number assay for in situ evaluation of transcriptome quality
Linda Kvastad, Konstantin Carlberg, Ludvig Larsson, Eva Gracia Villacampa, Alexander Stuckey, et al.
(2021) Communications Biology, 4
Journal articleSpatial deconvolution of HER2-positive breast cancer delineates tumor-associated cell type interactions
Alma Andersson, Ludvig Larsson, Linnea Stenbeck, Fredrik Salmén, Anna Ehinger, et al.
(2021) Nature Communications, 12
Journal articleThe predictive ability of the 313 variant–based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant
I.M.M. Lakeman, Åke Borg, Marjanka K. Schmidt
(2021) Genetics in Medicine, 23 p.1726-1737
Journal articleBreast cancer survival in Nordic BRCA2 mutation carriers—unconventional association with oestrogen receptor status
Elinborg J. Olafsdottir, Ake Borg, Maj Britt Jensen, Anne Marie Gerdes, Anna L.V. Johansson, et al.
(2020) British Journal of Cancer, 123 p.1608-1615
Journal articleRetrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
Matthew H. Bailey, William U. Meyerson, Lewis Jonathan Dursi, Liang Bo Wang, Guanlan Dong, et al.
(2020) Nature Communications, 11
Journal articleThe mutational landscape of the SCAN‐B real‐world primary breast cancer transcriptome
Christian Brueffer, Sergii Gladchuk, Christof Winter, Johan Vallon-Christersson, Cecilia Hegardt, et al.
(2020) EMBO Molecular Medicine, 12
Journal articleSex differences in oncogenic mutational processes
Constance H. Li, Stephenie D. Prokopec, Ren X. Sun, Fouad Yousif, Nathaniel Schmitz, et al.
(2020) Nature Communications, 11
Journal articleAbstract CT074: Pre-existing ESR1 mutations in early-stage primary breast cancer predict failure of endocrine therapy and poor survival
Malin Dahlgren, Anthony George, Christian Brueffer, Sergii Gladchuk, Yilun Chen, et al.
(2020) Cancer research. Supplement, 80
Conference paper: abstractIntegrating spatial gene expression and breast tumour morphology via deep learning
Bryan He, Ludvig Bergenstråhle, Linnea Stenbeck, Abubakar Abid, Alma Andersson, et al.
(2020) Nature Biomedical Engineering, 4 p.827-834
Journal articlePrognostic implications of the expression levels of different immunoglobulin heavy chain-encoding RNAs in early breast cancer
Christer Larsson, Anna Ehinger, Sofia Winslow, Karin Leandersson, Marie Klintman, et al.
(2020) npj Breast Cancer, 6
Journal articleTranscriptome-wide association study of breast cancer risk by estrogen-receptor status.
Helian Feng, Åke Borg, Håkan Olsson, Carolina Ellberg
(2020) Genetic Epidemiology, 44 p.442-468
Journal articleAnalysis of fusion transcripts indicates widespread deregulation of snoRNAs and their host genes in breast cancer
Helena Persson, Rolf Søkilde, Jari Häkkinen, Johan Vallon-Christersson, Felix Mitelman, et al.
(2020) International Journal of Cancer, 146 p.3343-3353
Journal articleDefining the mutational landscape of 3,217 primary breast cancer transcriptomes through large-scale RNA-seq within the Sweden Cancerome Analysis Network: Breast Project (SCAN-B; NCT03430492).
Christian Brueffer, Sergii Gladchuk, Christof Winter, Johan Vallon-christersson, Cecilia Hegardt, et al.
(2020) Journal of Clinical Oncology, 38 p.518-518
Conference paper: abstractCancer risks associated with germline PALB2 pathogenic variants : An international study of 524 families
Xin Yang, Goska Leslie, Alicja Doroszuk, Sandra Schneider, Jamie Allen, et al.
(2020) Journal of Clinical Oncology, 38 p.674-685
Journal articleDisruption of chromatin folding domains by somatic genomic rearrangements in human cancer
Kadir C Akdemir, Victoria T Le, Sahaana Chandran, Yilong Li, Roel G Verhaak, et al.
(2020) Nature Genetics, 52 p.294-305
Journal articleButler enables rapid cloud-based analysis of thousands of human genomes
Sergei Yakneen, Sebastian M Waszak, Michael Gertz, Jan O Korbel
(2020) Nature Biotechnology, 38 p.288-292
Journal articlePan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
Bernardo Rodriguez-Martin, Eva G Alvarez, Adrian Baez-Ortega, Jorge Zamora, Fran Supek, et al.
(2020) Nature Genetics, 52 p.306-319
Journal articleComprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
Isidro Cortés-Ciriano, Jake June-Koo Lee, Ruibin Xi, Dhawal Jain, Youngsook L Jung, et al.
(2020) Nature Genetics, 52 p.331-341
Journal articleComprehensive molecular characterization of mitochondrial genomes in human cancers
Yuan Yuan, Young Seok Ju, Youngwook Kim, Jun Li, Yumeng Wang, et al.
(2020) Nature Genetics, 52 p.342-352
Journal articleThe landscape of viral associations in human cancers
Marc Zapatka, Ivan Borozan, Daniel S Brewer, Murat Iskar, Adam Grundhoff, et al.
(2020) Nature Genetics, 52 p.320-330
Journal articleWhole-genome sequencing of triple negative breast cancers in a standard population-based clinical setting
Johan Staaf, Dominik Glodzik, Ana Bosch Campos, Johan Vallon-Christersson, Christel Reuterswärd, et al.
(2020) Breast Cancer Research and Treatment, 180 p.531-532
Conference paper: abstractPan-cancer analysis of whole genomes
Peter J. Campbell, Markus Ringnér, Jiashan Zhang
(2020) Nature, 578 p.82-93
Journal articleGenomic footprints of activated telomere maintenance mechanisms in cancer
Lina Sieverling, Chen Hong, Sandra D Koser, Philip Ginsbach, Kortine Kleinheinz, et al.
(2020) Nature Communications, 11
Journal articlePathway and network analysis of more than 2500 whole cancer genomes
Matthew A Reyna, David Haan, Marta Paczkowska, Lieven P C Verbeke, Miguel Vazquez, et al.
(2020) Nature Communications, 11
Journal articleReconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig
Yulia Rubanova, Ruian Shi, Caitlin F Harrigan, Roujia Li, Jeff Wintersinger, et al.
(2020) Nature Communications, 11
Journal articleCombined burden and functional impact tests for cancer driver discovery using DriverPower
Shimin Shuai, Steven Gallinger, Lincoln D Stein
(2020) Nature Communications, 11 p.734-734
Journal articleCancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis
Joana Carlevaro-Fita, Andrés Lanzós, Lars Feuerbach, Chen Hong, David Mas-Ponte, et al.
(2020) Communications Biology, 3
Journal articleDivergent mutational processes distinguish hypoxic and normoxic tumours
Vinayak Bhandari, Constance H Li, Robert G Bristow, Paul C Boutros
(2020) Nature Communications, 11
Journal articleIntegrative pathway enrichment analysis of multivariate omics data
Marta Paczkowska, Jonathan Barenboim, Nardnisa Sintupisut, Natalie S Fox, Helen Zhu, et al.
(2020) Nature Communications, 11
Journal articleA deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns
Wei Jiao, Gurnit Atwal, Paz Polak, Rosa Karlic, Edwin Cuppen, et al.
(2020) Nature Communications, 11
Journal articleHigh-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations
Yiqun Zhang, Fengju Chen, Nuno A Fonseca, Yao He, Masashi Fujita, et al.
(2020) Nature Communications, 11
Journal articleInferring structural variant cancer cell fraction
Marek Cmero, Ke Yuan, Cheng Soon Ong, Jan Schröder, Niall M Corcoran, et al.
(2020) Nature Communications, 11
Journal articleAbstract P1-18-10: Preoperative treatment of HER2-positive breast cancer in South Sweden. A retrospective, comprehensive survey of neo-adjuvant treated HER2-positve breast cancer in the SCAN-B project 2010-2017
Martin Malmberg, Christer Larsson, Johan Vallon-Christersson, Anna Ehinger, Cecilia Hegardt, et al.
(2020) Cancer research. Supplement, 80 p.1-18
Conference paper: abstractGenomic basis for RNA alterations in cancer
Claudia Calabrese, Natalie R Davidson, Deniz Demircioğlu, Nuno A Fonseca, Yao He, et al.
(2020) Nature, 578 p.129-136
Journal articleAnalyses of non-coding somatic drivers in 2,658 cancer whole genomes
Esther Rheinbay, Morten Muhlig Nielsen, Federico Abascal, Jeremiah A Wala, Ofer Shapira, et al.
(2020) Nature, 578 p.102-111
Journal articleThe evolutionary history of 2,658 cancers
Moritz Gerstung, Clemency Jolly, Ignaty Leshchiner, Stefan C Dentro, Santiago Gonzalez, et al.
(2020) Nature, 578 p.122-128
Journal articlePatterns of somatic structural variation in human cancer genomes
Yilong Li, Nicola D Roberts, Jeremiah A Wala, Ofer Shapira, Steven E Schumacher, et al.
(2020) Nature, 578 p.112-121
Journal articleThe repertoire of mutational signatures in human cancer
Ludmil B Alexandrov, Jaegil Kim, Nicholas J Haradhvala, Mi Ni Huang, Alvin Wei Tian Ng, et al.
(2020) Nature, 578 p.94-101
Journal articleThe Mutational Landscape of the SCAN-B Real-World Primary Breast Cancer Transcriptome
Christian Brueffer, Sergii Gladchuk, Christof Winter, Johan Vallon-Christersson, Cecilia Hegardt, et al.
(2020)
PreprintSubstantial intrinsic variability in chemoradiosensitivity of newly established anaplastic thyroid cancer cell-lines
Sigurdur Gretarsson, Alexander Nygren, Ann H Rosendahl, Nektaria Mylona, Elisabeth Kjellén, et al.
(2020) Acta Oto-Laryngologica, 140 p.337-343
Journal articleFine-mapping of 150 breast cancer risk regions identifies 191 likely target genes
Laura Fachal, Åke Borg, Håkan Olsson, Alison M Dunning
(2020) Nature Genetics, 52 p.56-73
Journal articleMale Breast Carcinoma after Irradiation and Long-Term Phenothiazine Exposure : A Case Report
Ragnar Hultborn, Toshima Z. Parris, Khalil Helou, Åke Borg, Shahin De Lara, et al.
(2020) Case Reports in Oncology, 13 p.956-961
Journal articleSpatial Deconvolution of HER2-positive Breast Tumors Reveals Novel Intercellular Relationships
Alma Andersson, Ludvig Larsson, Linnea Stenbeck, Fredrik Salmén, Anna Ehinger, et al.
(2020)
OtherAssociation of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness
Vivek L. Patel, Åke Borg, Hans Ehrencrona, Timothy R. Rebbeck
(2020) Cancer Research, 80 p.624-638
Journal articlePolygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants
Andrew D. Barnes, Åke Borg, A.C. Antoniou
(2020) Genetics in Medicine, 22 p.1653-1666
Journal articleOvarian and Breast Cancer Risks Associated With Pathogenic Variants in RAD51C and RAD51D
Xin Yang, Hans Ehrencrona, Åke Borg, Anders Kvist, Antonis C Antoniou
(2020) Journal of the National Cancer Institute, 112 p.1242-1250
Journal articleComprehensive molecular comparison of BRCA1 hypermethylated and BRCA1 mutated triple negative breast cancers
Dominik Glodzik, Ana Bosch, Johan Hartman, Mattias Aine, Johan Vallon-Christersson, et al.
(2020) Nature Communications, 11
Journal articleCross comparison and prognostic assessment of breast cancer multigene signatures in a large population-based contemporary clinical series
Johan Vallon-Christersson, Jari Häkkinen, Cecilia Hegardt, Lao Saal, Christer Larsson, et al.
(2019) Scientific Reports, 9
Journal articlePrediction of lymph node metastasis in breast cancer by gene expression and clinicopathological models: Development and validation within a population based cohort.
Looket Dihge, Johan Vallon-Christersson, Cecilia Hegardt, Lao Saal, Jari Häkkinen, et al.
(2019) Clinical Cancer Research, 25 p.6368-6381
Journal articleRefinement of breast cancer molecular classification by miRNA expression profiles
Rolf Søkilde, Helena Persson, Anna Ehinger, Anna Chiara Pirona, Mårten Fernö, et al.
(2019) BMC Genomics, 20
Journal articleFunctional characterization of novel germline TP53 variants in Swedish families
Pedram Kharaziha, Sophia Ceder, Olga Axell, Moritz Krall, Omid Fotouhi, et al.
(2019) Clinical Genetics, 96 p.216-225
Journal articlePrevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort
Jingmei Li, Wei Xiong Wen, Martin Eklund, Anders Kvist, Mikael Eriksson, et al.
(2019) International Journal of Cancer, 144 p.1195-1204
Journal articleWritten pretest information and germline BRCA1/2 pathogenic variant testing in unselected breast cancer patients : predictors of testing uptake
Martin P. Nilsson, Erik D. Nilsson, Barbro Silfverberg, Åke Borg, Niklas Loman
(2019) Genetics in Medicine, 21 p.89-96
Journal articleHigh patient satisfaction with a simplified BRCA1/2 testing procedure : long-term results of a prospective study
Martin P. Nilsson, Erik D. Nilsson, Åke Borg, Yvonne Brandberg, Barbro Silfverberg, et al.
(2019) Breast Cancer Research and Treatment, 173 p.313-318
Journal articleGenome-wide association and transcriptome studies identify target genes and risk loci for breast cancer
Manuel A. Ferreira, Åke Borg, Carolina Ellberg, Håkan Olsson
(2019) Nature Communications, 10
Journal articleAlternative splicing and ACMG-AMP-2015-based classification of PALB2 genetic variants : An ENIGMA report
Irene Lopez-Perolio, Raphaël Leman, Raquel Behar, Vanessa Lattimore, John F. Pearson, et al.
(2019) Journal of Medical Genetics, 56 p.453-460
Journal articleMendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers
Frank Qian, Åke Borg, Dezheng Huo
(2019) British Journal of Cancer
Journal articleHigh-definition spatial transcriptomics for in situ tissue profiling
Sanja Vickovic, Gökcen Eraslan, Fredrik Salmén, Johanna Klughammer, Linnea Stenbeck, et al.
(2019) Nature Methods, 16 p.987-990
Journal articleWhole-genome sequencing of triple-negative breast cancers in a population-based clinical study
Johan Staaf, Dominik Glodzik, Ana Bosch, Johan Vallon-Christersson, Christel Reuterswärd, et al.
(2019) Nature Medicine, 25 p.1526-1533
Journal articleLarge scale multifactorial likelihood quantitative analysis of BRCA1 and BRCA2 variants : An ENIGMA resource to support clinical variant classification
Michael T Parsons, Emma Tudini, Hongyan Li, Eric Hahnen, Barbara Wappenschmidt, et al.
(2019) Human Mutation , p.1557-1578
Journal articleGermline mutations in BRCA1 and BRCA2 incidentally revealed in a biobank research study : experiences from re-contacting mutation carriers and relatives
Martin P. Nilsson, Monica Emmertz, Ulf Kristoffersson, Åke Borg, Christer Larsson, et al.
(2018) Journal of Community Genetics, 9 p.201-208
Journal articleMultidimensional transcriptomics provides detailed information about immune cell distribution an identity in HER2+ breast tumors
Fredrik Salmén, Sanja Vickovic, Ludvig Larsson, Linnea Stenbeck, Johan Vallon-Christersson, et al.
(2018) BioRxiv
PreprintClinical Value of RNA Sequencing–Based Classifiers for Prediction of the Five Conventional Breast Cancer Biomarkers: A Report From the Population-Based Multicenter Sweden Cancerome Analysis Network—Breast Initiative
Christian Brueffer, Johan Vallon-Christersson, Dorthe Grabau, Anna Ehinger, Jari Häkkinen, et al.
(2018) JCO Precision Oncology, 2 p.1-18
Journal articleAbstract P2-02-09: Breast cancer subtype distribution and circulating tumor DNA in response to neoadjuvant chemotherapy: Experiences from a preoperative cohort within SCAN-B
Niklas Loman, Yilun Chen, Kristina Aaltonen, Christian Brueffer, Anthony George, et al.
(2018) Cancer research. Supplement, 78
Conference paper: abstractAbstract P1-06-01: Putting multigene signatures to the test: Prognostic assessment in population-based contemporary clinical breast cancer
Johan Staaf, Johan Vallon-Christersson, Jari Häkkinen, Lao Saal, Cecilia Hegardt, et al.
(2018) Cancer research. Supplement, 78
Conference paper: abstractAbstract P4-09-03: On the development and clinical value of RNA-sequencing-based classifiers for prediction of the five conventional breast cancer biomarkers: A report from the population-based multicenter SCAN-B study
Christian Brueffer, Johan Vallon-Christersson, Dorthe Grabau, Anna Ehinger, Jari Häkkinen, et al.
(2018) Cancer research. Supplement, 78
Conference paper: abstractAbstract P3-02-02: Concordance between immunohistochemical and gene-expression based subtyping of early breast cancer using core needle biopsies and surgical specimens - experices from SCAN-B
G Morgan, Christer Larsson, Balázs Tahin, Johan Vallon-Christersson, Jari Häkkinen, et al.
(2018) Cancer research. Supplement, 78
Conference paper: abstractMinimizing inequality in access to precision medicine in breast cancer by real-time population-based molecular analysis in the SCAN-B initiative
Lisa Rydén, Niklas Loman, Christer Larsson, Cecilia Hegardt, Johan Vallon-Christersson, et al.
(2018) British Journal of Surgery, 105 p.158-168
Journal articleThe BRCA1 c. 5096G>A p.Arg1699Gln (R1699Q) intermediate risk variant : Breast and ovarian cancer risk estimation and recommendations for clinical management from the ENIGMA consortium
Setareh Moghadasi, Huong D. Meeks, Maaike P G Vreeswijk, Linda A.M. Janssen, Åke Borg, et al.
(2018) Journal of Medical Genetics, 55 p.15-20
Journal articleIndividuals with FANCM biallelic mutations do not develop Fanconi anemia, but show risk for breast cancer, chemotherapy toxicity and may display chromosome fragility
Irene Catucci, Ana Osorio, Brita Arver, Guido Neidhardt, Massimo Bogliolo, et al.
(2018) Genetics in Medicine, 20 p.452-457
Journal articleGene-panel testing of breast and ovarian cancer patients identifies a recurrent RAD51C duplication
L. M. Pelttari, H. Shimelis, H. Toiminen, A. Kvist, T. Törngren, et al.
(2018) Clinical Genetics, 93 p.595-602
Journal articleBRCAsearch : written pre-test information and BRCA1/2 germline mutation testing in unselected patients with newly diagnosed breast cancer
Martin P. Nilsson, Therese Törngren, Karin Henriksson, Ulf Kristoffersson, Anders Kvist, et al.
(2018) Breast Cancer Research and Treatment, 168 p.117-126
Journal articleAccuracy of self-reported family history of cancer, mutation status and tumor characteristics in patients with early onset breast cancer
Annelie Augustinsson, Carolina Ellberg, Ulf Kristoffersson, Åke Borg, Håkan Olsson
(2018) Acta Oncologica, 57 p.595-603
Journal articleFrequent miRNA-convergent fusion gene events in breast cancer
Helena Persson, Rolf Søkilde, Jari Häkkinen, Anna Chiara Pirona, Johan Vallon-Christersson, et al.
(2017) Nature Communications, 8
Journal articleMyoepithelium assessment with p63 immunostaining in formalinfixed paraffin-embedded breast cancer tissue pre-treated with RNA-later
Anna Ehinger, Inger Remse, Kristina Lövgren, Cecilia Hegardt, Jari Häkkinen, et al.
(2017) Virchows Archiv, 471 p.299-299
Conference paper: abstractFANCM mutation c.5791C>T is a risk factor for triple-negative breast cancer in the Finnish population
Johanna I. Kiiski, Anna Tervasmäki, Liisa M Pelttari, Sofia Khan, Tuomo Mantere, et al.
(2017) Breast Cancer Research and Treatment, 166 p.217-226
Journal articleEvaluation of polygenic risk scores for breast and ovarian cancer risk prediction in BRCA1 and BRCA2 mutation carriers
Karoline B. Kuchenbaecker, Lesley McGuffog, Daniel Barrowdale, Andrew Lee, Penny Soucy, et al.
(2017) Journal of the National Cancer Institute, 109
Journal articleClinical framework for next generation sequencing based analysis of treatment predictive mutations and multiplexed gene fusion detection in non-small cell lung cancer
Kajsa Ericson Lindquist, Anna Karlsson, Per Levéen, Hans Brunnström, Christel Reuterswärd, et al.
(2017) Oncotarget, 8 p.34796-34810
Journal articleIdentification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer
Catherine M. Phelan, Karoline B. Kuchenbaecker, Jonathan P. Tyrer, Siddhartha P. Kar, Kate Lawrenson, et al.
(2017) Nature Genetics, 49 p.680-691
Journal articleCase-control analysis of truncating mutations in DNA damage response genes connects TEX15 and FANCD2 with hereditary breast cancer susceptibility
Tuomo Mantere, Anna Tervasmäki, Anna Nurmi, Katrin Rapakko, Saila Kauppila, et al.
(2017) Scientific Reports, 7
Journal articleHRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures
Helen R. Davies, Dominik Glodzik, Sandro Morganella, Lucy R. Yates, Johan Staaf, et al.
(2017) Nature Medicine, 23 p.517-525
Journal articleExpanding the genotype–phenotype spectrum in hereditary colorectal cancer by gene panel testing
Anna Rohlin, Eva Rambech, Anders Kvist, Therese Törngren, Frida Eiengård, et al.
(2017) Familial Cancer, 16 p.195-203
Journal articleSomatic mutations reveal asymmetric cellular dynamics in the early human embryo
Young Seok Ju, Inigo Martincorena, Moritz Gerstung, Mia Petljak, Ludmil B. Alexandrov, et al.
(2017) Nature, 543 p.714-718
Journal articleCytohesin 1 regulates homing and engraftment of human hematopoietic stem and progenitor cells
Justyna Rak, Katie Foster, Kasia Potrzebowska, Mehrnaz Safaee Talkhoncheh, Natsumi Miharada, et al.
(2017) Blood, 129 p.950-958
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Journal articleCandidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers.
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Journal articleImpact of a paternal origin of germline BRCA1/2 mutations on the age at breast and ovarian cancer diagnosis in a Southern Swedish cohort.
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Journal articleCDKN2A-mutation hos en familie med arveligt malignt melanom
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Journal articleCancer-Associated Fibroblasts Expressing CXCL14 Rely upon NOS1-Derived Nitric Oxide Signaling for Their Tumor-Supporting Properties
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Journal articleGenome-wide DNA methylation analysis of lung carcinoma reveals one neuroendocrine and four adenocarcinoma epitypes associated with patient outcome.
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Journal articleGermline rearrangements in families with strong family history of glioma and malignant melanoma, colon, and breast cancer.
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Journal articleGain of chromosomal region 20q and loss of 18 discriminates between Lynch syndrome and familial colorectal cancer
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Journal articleContralateral breast cancer after radiotherapy among BRCA1 and BRCA2 mutation carriers: A WECARE Study Report
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Journal articleA BAP1 Mutation in a Danish Family Predisposes to Uveal Melanoma and Other Cancers
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Journal articleMultiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
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Journal articleMutual Exclusivity Analysis of Genetic and Epigenetic Drivers in Melanoma Identifies a Link Between p14(ARF) and RAR beta Signaling
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Journal articleAssociation Between BRCA1 and BRCA2 Mutations and Survival in Women With Invasive Epithelial Ovarian Cancer
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Journal articleThe Life History of 21 Breast Cancers
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Journal articlePrevalence of germline TP53 mutations and history of Li-Fraumeni syndrome in families with childhood adrenocortical tumors, choroid plexus tumors, and rhabdomyosarcoma: A population-based survey.
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Journal articleThe gene expression landscape of breast cancer is shaped by tumor protein p53 status and epithelial-mesenchymal transition
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Journal articleMutational Processes Molding the Genomes of 21 Breast Cancers
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Journal articleAmplification and overexpression of the ABCC3 (MRP3) gene in primary breast cancer
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Journal articleCharacterisation of amplification patterns and target genes at chromosome 11q13 in CCND1-amplified sporadic and familial breast tumours.
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Journal articleMolecular profiling reveals low- and high-grade forms of primary melanoma
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Journal articleThe retinoblastoma gene undergoes rearrangements in BRCA1-deficient basal-like breast cancer.
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Journal articleBRCA1 R1699Q variant displaying ambiguous functional abrogation confers intermediate breast and ovarian cancer risk
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Journal articleHigh-resolution genomic profiling of male breast cancer reveals differences hidden behind the similarities with female breast cancer
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Journal articleCD44 isoforms are heterogeneously expressed in breast cancer and correlate with tumor subtypes and cancer stem cell markers.
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Journal articleA BRCA2 mutation incorrectly mapped in the original BRCA2 reference sequence, is a common West Danish founder mutation disrupting mRNA splicing
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Journal articleExploring the link between MORF4L1 and risk of breast cancer
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Journal articleLandscape of somatic allelic imbalances and copy number alterations in HER2-amplified breast cancer
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Journal articleBreast tumors from CHEK2 1100delC-mutation carriers: genomic landscape and clinical implications
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Journal articleCommon alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers
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Journal articleGOBO: Gene Expression-Based Outcome for Breast Cancer Online.
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Journal articleCommon variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers
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Journal articleGenetic Variation at 9p22.2 and Ovarian Cancer Risk for BRCA1 and BRCA2 Mutation Carriers.
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Journal articleIdentification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene.
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Journal articleEndothelial Induced EMT in Breast Epithelial Cells with Stem Cell Properties
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Journal articleGenetic variants on chromosome 5p12 are associated with risk of breast cancer in African American women: the Black Women's Health Study
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Journal articleOral contraceptives and postmenopausal hormones and risk of contralateral breast cancer among BRCA1 and BRCA2 mutation carriers and noncarriers: the WECARE Study
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Journal articleImproving Surveillance and Quality of Life of BRCA Mutation Carriers.
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Journal articleFrequent alterations of the PI3K/AKT/mTOR pathways in hereditary nonpolyposis colorectal cancer.
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Journal articleCharacterization of BRCA1 and BRCA2 deleterious mutations and variants of unknown clinical significance in unilateral and bilateral breast cancer: the WECARE study.
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Journal articleCommon Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer
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Journal articleInternational network of cancer genome projects
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Journal articleGenomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics
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Journal articleMolecular subtypes of breast cancer are associated with characteristic DNA methylation patterns
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Journal articleGenome-wide search for breast cancer linkage in large Icelandic non-BRCA1/2 families
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Journal articleHigh-resolution genomic and expression analyses of copy number alterations in HER2-amplified breast cancer
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Journal articlePopulation-Based Study of the Risk of Second Primary Contralateral Breast Cancer Associated With Carrying a Mutation in BRCA1 or BRCA2.
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Journal articleMultiple metastases from cutaneous malignant melanoma patients may display heterogeneous genomic and epigenomic patterns.
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Journal articleIdentification of Subtypes in Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Reveals a Gene Signature Prognostic of Outcome.
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Journal articleGene Expression Profiling-Based Identification of Molecular Subtypes in Stage IV Melanomas with Different Clinical Outcome.
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Journal articleZoom-in array comparative genomic hybridization (aCGH) to detect germline rearrangements in cancer susceptibility genes.
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Journal articleSwedish CDKN2A mutation carriers do not present the atypical mole syndrome phenotype.
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Journal articleGenetic profiles distinguish different types of hereditary ovarian cancer.
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Journal articleGenetic profiles of gastroesophageal cancer: combined analysis using expression array and tiling array-comparative genomic hybridization
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Journal articleAnalysis of a set of missense, frameshift, and in-frame deletion variants of BRCA1
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Journal articleIDENTIFICATION OF NOVEL SECRETED TUMOR STROMA-DERIVED STIMULATORS OF PROSTATE CANCER GROWTH
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Conference paper: abstractMiRNA expression in urothelial carcinomas: Important roles of miR-10a, miR-222, miR-125b, miR-7 and miR-452 for tumor stage and metastasis, and frequent homozygous losses of miR-31.
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Journal articleA Comprehensive Model for DNA Repair Genes and Radiation in Second Breast Cancers: The WECARE Collaborative Study Group
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Conference paper: abstractGenomic alterations in coleorectal cencer in relationship to stage and survival assesed by tiling BAC array CGH
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Conference paper: abstractBRCA1 and BRCA2 mutations in Danish families with hereditary breast and/or ovarian cancer
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Journal articleBRCA1 and BRCA2 point mutations and large rearrangements in breast and ovarian cancer families in Northern Poland
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Journal articleThe BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions
A. C. Antoniou, A. P. Cunningham, J. Peto, D. G. Evans, F. Lalloo, et al.
(2008) British Journal of Cancer, 98 p.1457-1466
Journal articleDetection of submicroscopic constitutional chromosome aberrations in clinical diagnostics: a validation of the practical performance of different array platforms
Zhong-Fa Zhang, Claudia Ruivenkamp, Johan Staaf, Hongbo Zhu, Michela Barbaro, et al.
(2008) European Journal of Human Genetics, 16 p.786-792
Journal articleThe CD44(+)/CD24(-) phenotype is enriched in basal-like breast tumors
Gabriella Honeth, Pär-Ola Bendahl, Markus Ringnér, Lao Saal, Sofia Gruvberger, et al.
(2008) Breast Cancer Research, 10
Journal articleScreening for copy-number alterations and loss of heterozygosity in chronic lymphocytic leukemia-A comparative study of four differently designed, high resolution microarray platforms.
Rebeqa Gunnarsson, Johan Staaf, Mattias Jansson, Anne Marie Ottesen, Hanna Göransson, et al.
(2008) Genes, Chromosomes and Cancer, 47 p.697-711
Journal articleSegmentation-based detection of allelic imbalance and loss-of-heterozygosity in cancer cells using whole genome SNP arrays
Johan Staaf, David Lindgren, Johan Vallon-Christersson, Anders Isaksson, Hanna Goransson, et al.
(2008) Genome Biology, 9
Journal articleGene products of chromosome 11q and their association with CCND1 gene amplification and tamoxifen resistance in premenopausal breast cancer.
Katja Lundgren, Karolina Holm, Bo Nordenskjöld, Åke Borg, Göran Landberg
(2008) Breast Cancer Research, 10
Journal articleArray-CGH identifies cyclin D1 and UBCH10 amplicons in anaplastic thyroid carcinoma.
Jia-Jing Lee, Amy Y M Au, Theodoros Foukakis, Michela Barbaro, Nimrod Kiss, et al.
(2008) Endocrine-Related Cancer, 15 p.801-815
Journal articleDetection and precise mapping of germline rearrangements in BRCA1, BRCA2, MSH2, and MLH1 using zoom-in array comparative genomic hybridization (aCGH).
Johan Staaf, Therese Törngren, Eva Rambech, Ulla Johansson, Camilla Olsson, et al.
(2008) Human Mutation, 29 p.555-564
Journal articleHigher occurrence of childhood cancer in families with germline mutations in BRCA2, MMR and CDKN2A genes.
Susanne Magnusson, Åke Borg, Ulf Kristoffersson, Mef Nilbert, Thomas Wiebe, et al.
(2008) Familial Cancer, 7 p.331-337
Journal articleTiling resolution array CGH and high density expression profiling of urothelial carcinomas delineate genomic amplicons and candidate target genes specific for advanced tumors.
Markus Heidenblad, David Lindgren, Tord Jonson, Fredrik Liedberg, Srinivas Veerla, et al.
(2008) BMC Medical Genomics, 1
Journal articleNormalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios.
Johan Staaf, Johan Vallon-Christersson, David Lindgren, Gunnar Juliusson, Richard Rosenquist, et al.
(2008) BMC Bioinformatics, 9
Journal articleConfirmed cancer trends in families of patients with multiple cancers including cutaneous melanoma.
Kari Nielsen, Anna Måsbäck, Anna Bladström, Lotta Lundgren, Nils Jonsson, et al.
(2008) British Journal of Dermatology, 158 p.429-431
Journal articleRecurrent and multiple bladder tumors show conserved expression profiles.
David Lindgren, Sigurdur Gudjonsson, Kowan Ja Jee, Fredrik Liedberg, Sonja Aits, et al.
(2008) BMC Cancer, 8
Journal articleVariation of breast cancer risk among BRCA1/2 carriers
Colin B Begg, Robert W Haile, Åke Borg, Kathleen E Malone, Patrick Concannon, et al.
(2008) JAMA: The Journal of the American Medical Association, 299 p.194-201
Journal articleGenetic profiling differentiates second primary tumors from metastases in adult metachronous soft tissue sarcoma.
Josefin Fernebro, Ana Carneiro, Anders Rydholm, Henryk Domanski, Anna F Karlsson, et al.
(2008) Sarcoma, 2008
Journal articleRecurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair
Lao Saal, Sofia Gruvberger, Camilla Persson, Kristina Lövgren, Johan Staaf, et al.
(2008) Nature Genetics, 40 p.102-107
Journal articleArray-CGH reveals hidden gene dose changes in children with acute lymphoblastic leukaemia and a normal or failed karyotype by G-banding
Ekaterina Kuchinskaya, Mats Heyman, Ann Nordgren, Jacqueline Schoumans, Johan Staaf, et al.
(2008) British Journal of Haematology, 140 p.572-577
Journal articleTumor genome wide DNA alterations assessed by array CGH in patients with poor and excellent survival following operation for colorectal cancer
Kristina Lagerstedt-Robinson, Johan Staaf, Göran Jönsson, Elisabeth Hansson, Christina Lönnroth, et al.
(2007) Cancer Informatics, 3 p.55-341
Journal articlePoor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity
Lao Saal, Peter Johansson, Karolina Holm, Sofia Gruvberger, Qing-Bai She, et al.
(2007) Proceedings of the National Academy of Sciences, 104 p.7564-7569
Journal articleNon-coding antisense transcription detected by conventional and single-stranded cDNA microarray
Johan Vallon-Christersson, Johan Staaf, Anders Kvist, Patrik Medstrand, Åke Borg, et al.
(2007) BMC Genomics, 8
Journal articleRecurrent 10q22-q23 deletions: a genomic disorder on 10q associated with cognitive and behavioral abnormalities
Jorune Balciuniene, Ningping Feng, Kelly Iyadurai, Betsy Hirsch, Lawrence Charnas, et al.
(2007) American Journal of Human Genetics, 80 p.938-947
Journal articleHigh-resolution genomic profiles of breast cancer cell lines assessed by tiling BAC array comparative genomic hybridization.
Göran B Jönsson, Johan Staaf, Eleonor Olsson, Markus Heidenblad, Johan Vallon-Christersson, et al.
(2007) Genes, Chromosomes and Cancer, 46 p.543-558
Journal articleCYP17 genotype is associated with short menstrual cycles, early oral contraceptive use and BRCA mutation status in young healthy women
Maria Henningson, Ulla Johansson, Åke Borg, Håkan Olsson, Helena Jernström
(2007) Molecular Human Reproduction, 13 p.231-236
Journal articleThe molecular signature of MDS stem cells supports a stem-cell origin of 5q - myelodysplastic syndromes
Lars Nilsson, Patrik Edén, Eleonor Olsson, Robert Månsson, Ingbritt Åstrand-Grundström, et al.
(2007) Blood, 110 p.3005-3014
Journal articleRobust smooth segmentation approach for array CGH data analysis
J Huang, Arief Gusnanto, Kathleen O'Sullivan, Johan Staaf, Åke Borg, et al.
(2007) Bioinformatics, 23 p.2463-2469
Journal articleBasal-like phenotype is not associated with patient survival in estrogen-receptor-negative breast cancers
Mervi Jumppanen, Sofia Gruvberger, Paivikki Kauraniemi, Minna Tanner, Pär-Ola Bendahl, et al.
(2007) Breast Cancer Research, 9
Journal articleTiling resolution array CGH of dic(7;9)(p11 approximately 13;p11 approximately 13) in B-cell precursor acute lymphoblastic leukemia reveals clustered breakpoints at 7p11.2 approximately 12.1 and 9p13.1.
Catarina Lundin, Markus Heidenblad, Bodil Strömbeck, Åke Borg, R Hovland, et al.
(2007) Cytogenetic and Genome Research, 118 p.13-18
Journal articleTiling resolution array comparative genomic hybridization, expression and methylation analyses of dup(1q) in Burkitt lymphomas and pediatric high hyperdiploid acute lymphoblastic leukemias reveal clustered near-centromeric breakpoints and overexpression of genes in 1q22-32.3
Josef Davidsson, Anna Andersson, Kajsa Paulsson, Markus Heidenblad, Margareth Isaksson, et al.
(2007) Human Molecular Genetics, 16 p.2215-2225
Journal articleAbsence of the common IGF1 19 CA-repeat allele is more common among BRCA1 mutation carriers than among non-carriers from BRCA1 families.
Maria Henningson, Erika Bågeman, Therese Törngren, Åke Borg, Håkan Olsson, et al.
(2007) Familial Cancer, 6 p.445-452
Journal articleAURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: A consortium of investigators of modifiers of BRCA1/2 study
Fergus J. Couch, Olga Sinilnikova, Robert A. Vierkant, V. Shane Pankratz, Zachary S. Fredericksen, et al.
(2007) Cancer Epidemiology Biomarkers & Prevention, 16 p.1416-1421
Journal articleThe Wilms' tumor gene 1 (WT1) induces expression of the N-myc downstream regulated gene 2 (NDRG2)
Emelie Svensson, Karina Vidovic, Tor Olofsson, Johan Vallon-Christersson, Åke Borg, et al.
(2007) DNA and Cell Biology, 26 p.589-597
Journal articleMicroarray analysis of gliomas reveals chromosomal position-associated gene expression patterns and identifies potential immunotherapy targets.
Oscar Persson, Morten Krogh, Lao Saal, Elisabet Englund, Jian Liu, et al.
(2007) Journal of Neuro-Oncology, 85 p.11-24
Journal articleTiling-resolution array-CGH reveals the pattern of DNA copy number alterations in acute lymphoblastic leukemia with 21q amplification: the result of telomere dysfunction and breakage/fusion/breakage cycles?
E. Kuchinskaya, A. Nordgren, M. Heyman, J. Schoumans, M. Corcoran, et al.
(2007) Leukemia, 21 p.1327-1330
Journal article (letter)Cytogenetic characterization and gene expression profiling of the trastuzumab-resistant breast cancer cell line JIMT-1.
Karin Rennstam, Göran B Jönsson, Minna Tanner, Pär-Ola Bendahl, Johan Staaf, et al.
(2007) Cancer Genetics and Cytogenetics, 172 p.95-106
Journal articleGenomic profiling of malignant melanoma using tiling-resolution arrayCGH.
Göran B Jönsson, C Dahl, Johan Staaf, Therese Törngren, Pär-Ola Bendahl, et al.
(2007) Oncogene, 26 p.4738-4748
Journal articleComprehensive mutational analysis of a cohort of Swedish Cornelia de Lange syndrome patients
Jacqueline Schoumans, Josephine Wincent, Michela Barbaro, Tatjana Djureinovic, Paula Maguire, et al.
(2007) European Journal of Human Genetics, 15 p.143-149
Journal articleDuplication 16q12.1-q22.1 characterized by array CGH in a girl with spina bifida
Peter Gustavsson, Jacqueline Schoumans, Johan Staaf, Åke Borg, Magnus Nordenskjold, et al.
(2007) European Journal of Medical Genetics, 50 p.237-241
Journal articleDiscussion on the use of taxanes for treatment of breast cancers in BRCA1 mutations carriers
Pavel Elsakov, Lenka Foretova, Petr Goetz, Johannes W. B. de Groot, Winette T. A. van der Graaf, et al.
(2007) Hereditary Cancer in Clinical Practice, 5 p.119-143
Journal article (comment)Testosterone levels in relation to oral contraceptive use and the androgen receptor CAG and GGC length polymorphisms in healthy young women
M Hietala, Therese Törngren, Åke Borg, Håkan Olsson, Helena Jernström
(2007) Human Reproduction, 22 p.83-91
Journal articleEstrogen receptor beta expression is associated with tamoxifen response in ER alpha-negative breast carcinoma
Sofia Gruvberger, Pär-Ola Bendahl, Lao H Saal, Mervi Laakso, Cecilia Hegardt, et al.
(2007) Clinical Cancer Research, 13 p.1987-1994
Journal articleRAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability
Katri Heikkinen, Katrin Rapakko, Sanna-Maria Karppinen, Hannele Erkko, Sakari Knuutila, et al.
(2006) Carcinogenesis, 27 p.1593-1599
Journal articleGenomic profiling of bone and soft tissue tumors with supernumerary ring chromosomes using tiling resolution bacterial artificial chromosome microarrays.
Markus Heidenblad, Karolin Hansén Nord, Johan Staaf, Göran B Jönsson, Åke Borg, et al.
(2006) Oncogene, 25 p.7106-7116
Journal articleCharacterisation of dic(9;20)(p11-13;q11) in childhood B-cell precursor acute lymphoblastic leukaemia by tiling resolution array-based comparative genomic hybridisation reveals clustered breakpoints at 9p13.2 and 20q11.2
Jacqueline Schoumans, Bertil Johansson, Martin Corcoran, Ekaterina Kuchinskaya, Irina Golovleva, et al.
(2006) British Journal of Haematology, 135 p.492-499
Journal articleThe contribution of the hereditary nonpolyposis colorectal cancer syndrome to the development of ovarian cancer.
Susanne Malander, Eva Rambech, Ulf Kristoffersson, Britta Halvarsson, Mona Ridderheim, et al.
(2006) Gynecologic Oncology, 101 p.238-243
Journal articleDifferences in IGFBP-3 regulation between young healthy women from BRCAX families and those belonging to BRCA1/2 families.
Helena Jernström, Gunilla Sellberg, Åke Borg, Håkan Olsson
(2006) European Journal of Cancer Prevention, 15 p.233-241
Journal articleGene expression profiles relate to SS18/SSX fusion type in synovial sarcoma
Josefin Fernebro, Princy Francis, Patrik Edén, Åke Borg, Ioannis Panagopoulos, et al.
(2006) International Journal of Cancer, 118 p.1165-1172
Journal articleInsulin-like growth factor-1 genotype predicts breast volume after pregnancy and hormonal contraception and is associated with circulating insulin-like growth factor-1 levels: implications for risk of early-onset breast cancer in young women from hereditary breast cancer families.
Helena Jernström, Therese Törngren, Erika Bågeman, Åke Borg, Håkan Olsson
(2006) International Journal of Gynecological Cancer, 16 p.497-497
Journal articleIncreased risk of non-small cell lung cancer and frequency of somatic TP53 gene mutations in Pro72 carriers of TP53 Arg72Pro polymorphism
A Szymanowska, E Jassem, R Dziadziuszko, Åke Borg, J Limon, et al.
(2006) Lung Cancer, 52 p.9-14
Journal articlep53 mutation and cyclin D1 amplification correlate with cisplatin sensitivity in xenografted human squamous cell carcinomas from head and neck.
Eva Henriksson, Bo Baldetorp, Åke Borg, Elisabeth Kjellén, Jan Åkervall, et al.
(2006) Acta Oncologica, 45 p.300-305
Journal articleHigh-risk melanoma susceptibility genes and pancreatic cancer, neural system tumors, and uveal melanoma across GenoMEL
Alisa M. Goldstein, May Chan, Mark Harland, Elizabeth M. Gillanders, Nicholas K. Hayward, et al.
(2006) Cancer Research, 66 p.9818-9828
Journal articleNordic collaborative study of the BARD1 Cys557Ser allele in 3956 patients with cancer: enrichment in familial BRCA1/BRCA2 mutation-negative breast cancer but not in other malignancies
S. -M. Karppinen, R. B. Barkardottir, Katja Harbst, T. Sydenham, K. Syrjakoski, et al.
(2006) Journal of Medical Genetics, 43 p.856-862
Journal articleCHEK2 1100delC in patients with metachronous cancers of the breast and the colorectum
Anna Isinger Ekstrand, M Bhat, Åke Borg, Mef Nilbert
(2006) BMC Cancer, 6
Journal articleIdentification of cryptic aberrations and characterization of translocation breakpoints using array CGH in high hyperdiploid childhood acute lymphoblastic leukemia.
Kajsa Paulsson, Markus Heidenblad, Helena Mörse, Åke Borg, Thoas Fioretos, et al.
(2006) Leukemia, 20 p.2002-2007
Journal articleCHEK2*1100delC is not an important high-risk gene in families with hereditary prostate cancer in southern Sweden
M Wagenius, Åke Borg, L Johansson, Aleksander Giwercman, Ola Bratt
(2006) Scandinavian Journal of Urology and Nephrology, 40 p.23-25
Journal articleArray-based comparative genomic hybridization characterization of cytogenetically polyclonal myeloid malignancies.
Josef Davidsson, Markus Heidenblad, Åke Borg, Bertil Johansson
(2006) Cancer Genetics and Cytogenetics, 169 p.179-180
Journal article (letter)High-resolution genome-wide array-based comparative genome hybridization reveals cryptic chromosome changes in AML and MDS cases with trisomy 8 as the sole cytogenetic aberration.
Kajsa Paulsson, Markus Heidenblad, Bodil Strömbeck, Johan Staaf, Göran B Jönsson, et al.
(2006) Leukemia, 20 p.840-846
Journal articleRecruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype.
Linda Holmquist Mengelbier, Erik Fredlund, Tobias Löfstedt, Rosa Noguera, Samuel Navarro, et al.
(2006) Cancer Cell, 10 p.413-423
Journal articleMolecular characterization of early-stage bladder carcinomas by expression profiles, FGFR3 mutation status, and loss of 9q.
David Lindgren, Fredrik Liedberg, Anna Andersson, G Chebil, Sigurdur Gudjonsson, et al.
(2006) Oncogene, 25 p.2685-2696
Journal articleChromosome 5 imbalance mapping in breast tumors from BRCA1 and BRCA2 mutation carriers and sporadic breast tumors
Hrefna K. Johannsdottir, Göran B Jönsson, Gudrun Johannesdottir, Bjarni A. Agnarsson, Hannaleena Eerola, et al.
(2006) International Journal of Cancer, 119 p.1052-1060
Journal articleHemizygosity for chromosome 2q14.2-q22.1 spanning the GLI2 and PROC genes associated with growth hormone deficiency, polydactyly, deep vein thrombosis and urogenital abnormalities
P Gustavsson, J Schoumans, Johan Staaf, Göran B Jönsson, F Carlsson, et al.
(2006) Clinical Genetics, 69 p.441-443
Journal article (letter)Protein Expression Profiling of Hereditary Breast Cancer
Sofia Bengtsson, Morten Krogh, Johan Vallon-Christersson, Åke Borg, Peter James
(2006)
Conference paper: abstractProtein Expression Profiling of Hereditary Breast Cancer
Sofia Bengtsson, Morten Krogh, Johan Vallon-Christersson, Åke Borg, Peter James
(2006)
Conference paper: abstractDistinct genomic profiles in hereditary breast tumors identified by array-based comparative genomic hybridization.
Göran B Jönsson, Tara L Naylor, Johan Vallon-Christersson, Johan Staaf, Jia Huang, et al.
(2005) Cancer Research, 65 p.7612-7621
Journal articleClassification of BRCA1 missense variants of unknown clinical significance
C M Phelan, V Dapic, B Tice, R Favis, E Kwan, et al.
(2005) Journal of Medical Genetics, 42 p.138-146
Journal articleInsulin-like growth factor-1 (IGF1) genotype predicts breast volume after pregnancy and hormonal contraception and is associated with circulating IGF-1 levels: implications for risk of early-onset breast cancer in young women from hereditary breast cancer families.
Helena Jernström, Therese Törngren, Erika Bågeman, Åke Borg, Håkan Olsson
(2005) British Journal of Cancer, 92 p.857-866
Journal articleIntratumor versus intertumor heterogeneity in gene expression profiles of soft-tissue sarcomas.
Princy Francis, Josefin Fernebro, Patrik Edén, Anna Laurell, Anders Rydholm, et al.
(2005) Genes, Chromosomes and Cancer, 43 p.302-308
Journal articleDetection and delineation of an unusual 17p11.2 deletion by array-CGH and refinement of the Smith-Magenis syndrome minimum deletion to similar to 650 kb
J Schoumans, Johan Staaf, Göran B Jönsson, J Rantala, K S Zimmer, et al.
(2005) European Journal of Medical Genetics, 48 p.290-300
Journal articleGene expression profiling of leukemic cell lines reveals conserved molecular signatures among subtypes with specific genetic aberrations
Anna Andersson, Patrik Edén, David Lindgren, Jens Nilsson, Carin Lassen, et al.
(2005) Leukemia, 19 p.1042-1050
Journal articleBreast and ovarian cancer risks to carriers of the BRCA1 5382insC and 185delAG and BRCA2 6174delT mutations: a combined analysis of 22 population based studies
A C Antoniou, P D P Pharoah, S Narod, H A Risch, J E Eyfjord, et al.
(2005) Journal of Medical Genetics, 42 p.602-603
Journal articleAnaliza rokowniczego znaczenia mutacji genu TP53 u chorych na niedrobnokomorkowego raka pluca
Amelia Szymanowska, Ewa Jassem, Rafal Dziadziuszko, Marcin Skrzypski, Grazyna Kobierska-Gulida, et al.
(2005) Pneumonologia i Alergologia Polska, 73 p.264-269
Journal articleCytokeratin 5/14-positive breast cancer: true basal phenotype confined to BRCA1 tumors
M Laakso, Niklas Loman, Åke Borg, J Isola
(2005) Modern Pathology, 18 p.1321-1328
Journal articlePromoter usage of BRCA1-IRIS
Anders Kvist, Carlos Rovira, Åke Borg, Patrik Medstrand
(2005) Nature Cell Biology, 7 p.325-326
Journal article (letter)Mapping of a novel ocular and cutaneous malignant melanoma susceptibility locus to chromosome 9q21.32.
Göran B Jönsson, Pär-Ola Bendahl, Therese Törngren, Azra Kurbasic, Johan Staaf, et al.
(2005) Journal of the National Cancer Institute, 97 p.1377-1382
Journal articlePIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma
Lao Saal, Karolina Holm, M Maurer, L Memeo, T Su, et al.
(2005) Cancer Research, 65 p.2554-2559
Journal articleImpact of teenage oral contraceptive use in a population-based series of early-onset breast cancer cases who have undergone BRCA mutation testing
Helena Jernström, Niklas Loman, OT Johannsson, Åke Borg, Håkan Olsson
(2005) European Journal of Cancer, 41 p.2312-2320
Journal articleHigh follicular phase luteinizing hormone levels in young healthy BRCA1 mutation carriers: Implications for breast and ovarian cancer risk.
Helena Jernström, Åke Borg, Håkan Olsson
(2005) Molecular Genetics and Metabolism, 86 p.320-327
Journal articlePredicting continuous values of prognostic markers in breast cancer from microarray gene expression profiles.
Sofia Gruvberger, Patrik Edén, Markus Ringnér, Bo Baldetorp, Gunilla Chebil, et al.
(2004) Molecular Cancer Therapeutics, 3 p.161-168
Journal articleOne in 10 ovarian cancer patients carry germ line BRCA1 or BRCA2 mutations : results of a prospective study in Southern Sweden
S Malander, M Ridderheim, A Måsbäck, N Loman, U Kristoffersson, et al.
(2004) European Journal of Cancer, 40 p.422-428
Journal articleDeletions on chromosome 4 in sporadic and BRCA mutated tumors and association with pathological variables
HK Johannsdottir, G Johannesdottir, BA Agnarsson, H Eerola, A Arason, et al.
(2004) Anticancer research, 24 p.2681-2687
Journal articleA familial syndromic association between cutaneous malignant melanoma and neural system tumours: reply from authors
K. Nielsen, C. Ingvar, A. Måsbäck, J. Westerdahl, Å Borg, et al.
(2004) British Journal of Dermatology, 151 p.1279-1279
Journal article (letter)Loss of heterozygosity at BRCA2 in a ductal carcinoma in situ and three invasive breast carcinomas in a family with a germline BRCA2 mutation
M Thomassen, TA Kruse, KE Olsen, Åke Borg, AM Gerdes
(2004) Breast Cancer Research and Treatment, 87 p.273-276
Journal articleMelanoma and nonmelanoma skin cancer in patients with multiple tumours-evidence for new syndromes in a population-based study.
Kari Nielsen, Christian Ingvar, Anna Måsbäck, Johan Westerdahl, Åke Borg, et al.
(2004) British Journal of Dermatology, 150 p.531-536
Journal articleStaf50 is a novel p53 target gene conferring reduced clonogenic growth of leukemic U-937 cells.
Susanna Obad, Hans Brunnström, Johan Vallon-Christersson, Åke Borg, Kristina Drott, et al.
(2004) Oncogene, 23 p.4050-4059
Journal articleHuman neuroblastoma cells exposed to hypoxia: induction of genes associated with growth, survival, and aggressive behavior.
Annika Jögi, Johan Vallon-Christersson, Linda Holmquist Mengelbier, Håkan Axelson, Åke Borg, et al.
(2004) Experimental Cell Research, 295 p.469-487
Journal articleBRCA2 mutations in 154 Finnish male breast cancer patients
K Syrjakoski, T Kuukasjarvi, K Waltering, Karin Haraldsson, A Auvinen, et al.
(2004) Neoplasia, 6 p.541-545
Journal articleExpression profiling to predict outcome in breast cancer: the influence of sample selection
Sofia Gruvberger, Markus Ringnér, Patrik Edén, Åke Borg, Mårten Fernö, et al.
(2003) Breast Cancer Research, 5 p.23-26
Journal articleMolecular classification of familial non-BRCA1/BRCA2 breast cancer
Ingrid Hedenfalk, Markus Ringnér, Amir Ben-Dor, Zohar Yakhini, Yidong Chen, et al.
(2003) Proceedings of the National Academy of Sciences, 100 p.2532-2537
Journal articlePatterns of chromosomal imbalances defines subgroups of breast cancer with distinct clinical features and prognosis. A study of 305 tumors by comparative genomic hybridization.
Karin Rennstam, Minna Ahlstedt-Soini, Bo Baldetorp, Pär-Ola Bendahl, Åke Borg, et al.
(2003) Cancer Research, 63 p.8861-8868
Journal articleBRCA1 and BRCA2 mutation analysis in breast-ovarian cancer families from northeastern Poland
Magdalena Perkowska, Izabela BroZek, Barbara Wysocka, Karin Haraldsson, Therese Törngren, et al.
(2003) Human Mutation, 21 p.553-554
Journal articlePredicting the future of breast cancer.
Åke Borg, Mårten Fernö, Carsten Peterson
(2003) Nature Medicine, 9 p.16-18
Journal article (letter)Lack of HIN-1 methylation in BRCAl-linked and "BRCA1-like" breast tumors
I Krop, P Maguire, J Lahti-Domenici, G Lodeiro, A Richardson, et al.
(2003) Cancer Research, 63 p.2024-2027
Journal articleAverage risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: A combined analysis of 22 studies
A Antoniou, PDP Pharoah, S Narod, HA Risch, JE Eyfjord, et al.
(2003) American Journal of Human Genetics, 72 p.1117-1130
Journal articleCancer incidence in relatives of a population-based set of cases of early-onset breast cancer with a known BRCA1 and BRCA2 mutation status
Niklas Loman, Anna Bladström, O Johannsson, Åke Borg, Håkan Olsson
(2003) Breast Cancer Research, 5 p.175-186
Journal article reviewChromosomal translocations involving 11q13 contribute to cyclin D1 overexpression in squamous cell carcinoma of the head and neck
Jan Åkervall, Åke Borg, Michael Dictor, Charlotte Jin, Yuesheng Jin, et al.
(2002) International Journal of Oncology, 20 p.45-52
Journal articleBRCA1 and BRCA2 mutations among breast cancer patients from the Philippines
MLD Matsuda, A Liede, E Kwan, CA Mapua, EMC Cutiongco, et al.
(2002) International Journal of Cancer, 98 p.596-603
Journal articleIncreased CpG methylation of the estrogen receptor gene in BRCA1-linked estrogen receptor-negative breast cancers
WB Archey, KA McEachern, M Robson, K Offit, SAJ Vaziri, et al.
(2002) Oncogene, 21 p.7034-7041
Journal articleA naturally occurring allele of BRCA1 coding for a temperature-sensitive mutant protein
T Worley, Johan Vallon-Christersson, B Billack, Åke Borg, ANA Monteiro
(2002) Cancer Biology & Therapy, 1 p.497-501
Journal articleSurvival in prospectively ascertained familial breast cancer: Analysis of a series stratified by tumour characteristics, BRCA mutations and oophorectomy
P Moller, Åke Borg, D G Evans, N Haites, MM Reis, et al.
(2002) International Journal of Cancer, 101 p.555-559
Journal articleBioarray software environment: a platform for comprehensive management and analysis of microarray data
Lao Saal, Carl Troein, Johan Vallon-Christersson, Sofia Gruvberger, Åke Borg, et al.
(2002) Genome Biology, 3 p.1-2002
Journal articleCancer Incidence in BRCA1 mutation carriers
D Thompson, DF Easton, Åke Borg, O Johannsson, Niklas Loman, et al.
(2002) Journal of the National Cancer Institute, 94 p.1358-1365
Journal articleA genomic map of a 6-Mb region at 13q21-q22 implicated in cancer development: identification and characterization of candidate genes
E Rozenblum, P Vahteristo, Therese Törngren, JT Bergthorsson, K Syrjakoski, et al.
(2002) Human Genetics, 110 p.111-121
Journal articleGene expression in inherited breast cancer
Ingrid Hedenfalk, Markus Ringnér, Jeffrey Trent, Åke Borg
(2002) Advances in Cancer Research, 84 p.1-34
Journal article reviewVariation in BRCA1 cancer risks by mutation position
Deborah Thompson, Douglas Easton, Åke Borg, Niklas Loman, O Johannsson, et al.
(2002) Cancer Epidemiology Biomarkers & Prevention, 11 p.329-336
Journal articleClinical and histopathological features of malignant melanoma in germline CDKN2A mutation families
Anna Måsbäck, Håkan Olsson, Johan Westerdahl, Therese Törngren, Åke Borg, et al.
(2002) Melanoma Research, 12 p.549-557
Journal articleTP53 protein expression analysis by luminometric immunoassay in comparison with gene mutation status and prognostic factors in early stage endometrial cancer
Anjila Koul, Pär-Ola Bendahl, Åke Borg, Mårten Fernö, MF Lidebring, et al.
(2002) International Journal of Gynecological Cancer, 12 p.362-371
Journal articleDistinct sets of gene alterations in endometrial carcinoma implicate alternate modes of tumorigenesis
Anjila Koul, R Willen, Pär-Ola Bendahl, Mef Nilbert, Åke Borg
(2002) Cancer, 94 p.2369-2379
Journal articleFamily history of breast and ovarian cancers and BRCA1 and BRCA2 mutations in a population-based series of early-onset breast cancer
N Loman, O Johannsson, U Kristoffersson, H Olsson, A Borg
(2001) Journal of the National Cancer Institute, 93 p.23-1215
Journal articleEstrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns
Sofia Gruvberger, Markus Ringnér, Yidong Chen, Sujatha Panavally, Lao Saal, et al.
(2001) Cancer Research, 61 p.5979-5984
Journal articleGene-expression profiles in hereditary breast cancer
I Hedenfalk, D Duggan, Y Chen, M Radmacher, M Bittner, et al.
(2001) New England Journal of Medicine, 344 p.48-539
Journal articleFunctional analysis of BRCA1 C-terminal missense mutations identified in breast and ovarian cancer families
J Vallon-Christersson, C Cayanan, K Haraldsson, N Loman, J T Bergthorsson, et al.
(2001) Human Molecular Genetics, 10 p.60-353
Journal articleHaplotype analysis and age estimation of the 113insR CDKN2A founder mutation in Swedish melanoma families
Jamileh Hashemi, Pär-Ola Bendahl, Therese Törngren, Anton Platz, Stig Linder, et al.
(2001) Genes, Chromosomes and Cancer, 31 p.107-116
Journal articleDNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis
Manel Esteller, Mario F. Fraga, Mingzhou Guo, Jesus Garcia-Foncillas, Ingrid Hedenfalk, et al.
(2001) Human Molecular Genetics, 10 p.3001-3007
Journal articleFirst BRCA1 and BRCA2 gene testing implemented in the health care system of Stockholm
Brita Arver, Åke Borg, Annika Lindblom
(2001) Genetic Testing, 5 p.41282-41282
Journal articleGenetic epidemiology of BRCA1 mutations in Norway
P. Moller, K. Heimdal, J. Apold, A. Fredriksen, Åke Borg, et al.
(2001) European Journal of Cancer, 37 p.2428-2434
Journal articleThe BRCA1 syndrome and other inherited breast or breast-ovarian cancers in a Norwegian prospective series
P Möller, Åke Borg, K Heimdal, J Apold, Johan Vallon-Christersson, et al.
(2001) European Journal of Cancer, 37 p.1027-1032
Journal articleBRCA1 and BRCA2 mutation status and cancer family history of Danish women affected with multifocal or bilateral breast cancer at a young age
J.T. Bergthorsson, B. Ejlertsen, J.H. Olsen, Åke Borg, K.V. Nielsen, et al.
(2001) Journal of Medical Genetics, 38 p.361-368
Journal articleRESPONSE: Re: High frequency of multiple melanomas and breast and pancreas carcinomas in CDKN2A mutation-positive melanoma families
Håkan Olsson, Harald Andersson, Anna Bladström, Åke Borg, Christian Ingvar, et al.
(2001) Journal of the National Cancer Institute, 93 p.324-325
Journal article (letter)Hereditary prostate cancer: a new piece of the puzzle.
Åke Borg
(2001) Nature Medicine, 7 p.153-155
Journal article (letter)Molecular and pathological characterization of inherited breast cancer.
Åke Borg
(2001) Seminars in Cancer Biology, 11 p.375-385
Journal articleDeletion mapping of chromosome segment 11q24-q25, exhibiting extensive allelic loss in early onset breast cancer
Massimilano Gentile, Åsa Wiman, Sten Thorstenson, Niklas Loman, Åke Borg, et al.
(2001) International Journal of Cancer, 92 p.208-213
Journal articleLow frequency of E-cadherin alterations in familial breast cancer
Sima Salahshor, Haixin Lei, Huagang Huo, Vessela N Kristensen, Niklas Loman, et al.
(2001) Breast Cancer Research, 3 p.199-207
Journal articleTwo BRCA1-positive epithelial ovarian tumors with metastases to the central nervous system: a case report
Anjila Koul, Niklas Loman, Susanne Malander, Åke Borg, Mona Ridderheim
(2001) Gynecologic Oncology, 80 p.399-402
Journal articleBRCA2 mutation in a family with hereditary prostate cancer
Henrik Grönberg, Anna-Karin Åhman, Monica Emanuelsson, Anders Bergh, Jan-Erik Damber, et al.
(2001) Genes, Chromosomes and Cancer, 30 p.299-301
Journal articleFrequent somatic loss of BRCA1 in breast tumours from BRCA2 germ-line mutation carriers and vice versa
S. Staff, J.J. Isola, O. Johannsson, Åke Borg, M.M. Tanner
(2001) British Journal of Cancer, 85 p.1201-1205
Journal articleSomatic frameshift alterations in mononucleotide repeat-containing genes in different tumor types from an HNPCC family with germline MSH2 mutation
M Planck, E Wenngren, Åke Borg, Håkan Olsson, M Nilbert
(2000) Genes, Chromosomes and Cancer, 29 p.33-39
Journal articleHigh frequency of multiple melanomas and breast and pancreas carcinomas in CDKN2A mutation-positive melanoma families
Åke Borg, T Sandberg, K Nilsson, O Johannsson, M Klinker, et al.
(2000) Journal of the National Cancer Institute, 92 p.6-1260
Journal articleA hypersensitive estrogen receptor-alpha mutation in premalignant breast lesions
S A Fuqua, C Wiltschke, Q X Zhang, A Borg, C G Castles, et al.
(2000) Cancer Research, 60 p.4026-4029
Journal articleCytogenetic heterogeneity and clonal evolution in synchronous bilateral breast carcinomas and their lymph node metastases from a male patient without any detectable BRCA2 germline mutation
A Adeyinka, F Mertens, L Bondeson, J P Garne, A Borg, et al.
(2000) Cancer Genetics and Cytogenetics, 118 p.42-47
Journal articleBRCA1 and BRCA2 mutations in ovarian cancer : Covariation with specific cytogenetic features
A. Koul, S. Malander, N. Loman, T. Pejovic, S. Heim, et al.
(2000) International Journal of Gynecological Cancer, 10 p.289-295
Journal articleSomatic deletions in hereditary breast cancers implicate 13q21 as a putative novel breast cancer susceptibility locus
T Kainu, S H Juo, R Desper, A A Schaffer, E Gillanders, et al.
(2000) Proceedings of the National Academy of Sciences, 97 p.9603-9608
Journal articlePrognosis and clinical presentation of BRCA2-associated breast cancer
Niklas Loman, O Johannsson, Pär-Ola Bendahl, N Dahl, Z Einbeigi, et al.
(2000) European Journal of Cancer, 36 p.1365-1373
Journal articleMYB oncogene amplification in hereditary BRCA1 breast cancer
P Kauraniemi, Ingrid Hedenfalk, Karin Persson, D J Duggan, Minna Tanner, et al.
(2000) Cancer Research, 60 p.5323-5328
Journal articlehMLH1, hMSH2 and hMSH6 mutations in hereditary non-polyposis colorectal cancer families from southern Sweden
M Planck, A Koul, E Fernebro, A Borg, U Kristoffersson, et al.
(1999) International Journal of Cancer, 83 p.197-202
Journal articleGuidelines for follow-up of women at high risk for inherited breast cancer : consensus statement from the Biomed 2 Demonstration Programme on Inherited Breast Cancer
P Møller, G Evans, N Haites, H Vasen, M M Reis, et al.
(1999) Disease Markers, 15 p.11-207
Journal articleCAG repeat length in the androgen receptor gene is related to age at diagnosis of prostate cancer and response to endocrine therapy, but not to prostate cancer risk
O Bratt, Åke Borg, U Kristoffersson, R Lundgren, Q X Zhang, et al.
(1999) British Journal of Cancer, 81 p.6-672
Journal articleReproductive factors in hereditary breast cancer
Helena Jernström, Oskar T Johannsson, Niklas Loman, Åke Borg, Håkan Olsson
(1999) Breast Cancer Research and Treatment, 58 p.295-301
Journal articleSomatic genetic alterations in BRCA2-associated and sporadic male breast cancer
M Tirkkonen, T Kainu, Niklas Loman, O T Johannsson, Håkan Olsson, et al.
(1999) Genes, Chromosomes and Cancer, 24 p.56-61
Journal articleIncidence of malignant tumours in relatives of BRCA1 and BRCA2 germline mutation carriers
Oskar Johannsson, Niklas Loman, Torgil Möller, Ulf Kristoffersson, Åke Borg, et al.
(1999) European Journal of Cancer, 35 p.1248-1257
Journal articleChromosomal aberrations in breast cancer: a comparison between cytogenetics and comparative genomic hybridization
Karin Persson, Nikos Pandis, Fredrik Mertens, Åke Borg, Bo Baldetorp, et al.
(1999) Genes, Chromosomes and Cancer, 25 p.115-122
Journal articleAmplification and overexpression of p40 subunit of eukaryotic translation initiation factor 3 in breast and prostate cancer
N N Nupponen, K Porkka, L Kakkola, Minna Tanner, Karin Persson, et al.
(1999) American Journal of Pathology, 154 p.1777-1783
Journal articleIsochromosome 17q in blast crisis of chronic myeloid leukemia and in other hematologic malignancies is the result of clustered breakpoints in 17p11 and is not associated with coding TP53 mutations
Thoas Fioretos, Bodil Strömbeck, Therese Törngren, Bertil Johansson, Rolf Billstrom, et al.
(1999) Blood, 94 p.225-232
Journal articlePregnancy-associated breast cancer in BRCA1 and BRCA2 germline mutation carriers
Oskar Thor Johannsson, Niklas Loman, Åke Borg, Håkan Olsson
(1998) The Lancet, 352 p.1359-1360
Journal article (letter)BRCA2 germ-line mutations are frequent in male breast cancer patients without a family history of the disease
K Haraldsson, N Loman, Qiu-Xia Zhang, O Johannsson, Håkan Olsson, et al.
(1998) Cancer Research, 58 p.71-1367
Journal articleBRCA1-positive patients are small for gestational age compared with their unaffected relatives
H Jernström, O Johannsson, A Borg, H Ivarsson, H Olsson
(1998) European Journal of Cancer, 34 p.71-368
Journal articleSurvival of BRCA1 breast and ovarian cancer patients : a population-based study from southern Sweden
O T Jóhannsson, J Ranstam, Åke Borg, Håkan Olsson
(1998) Journal of Clinical Oncology, 16 p.397-404
Journal articleSteroid receptors in hereditary breast carcinomas associated with BRCA1 or BRCA2 mutations or unknown susceptibility genes
Niklas Loman, Oskar Johannsson, Pär-Ola Bendahl, Åke Borg, Mårten Fernö, et al.
(1998) Cancer, 83 p.310-319
Journal articleDo BRCA1 mutations affect the ability to breast feed? Significantly shorter length of breast feeding among BRCA1 mutation carriers compared with their unaffected relatives.
Helena Jernström, L Johannsson, Åke Borg, Håkan Olsson
(1998) Breast, 7 p.320-324
Journal articleGenetic aberrations in hypodiploid breast cancer: frequent loss of chromosome 4 and amplification of cyclin D1 oncogene
M M Tanner, R A Karhu, N N Nupponen, Åke Borg, Bo Baldetorp, et al.
(1998) American Journal of Pathology, 153 p.191-199
Journal articleModerate frequency of BRCA1 and BRCA2 germ-line mutations in Scandinavian familial breast cancer
Sara Hakansson, O Johannsson, Ulla Johansson, G Sellberg, N Loman, et al.
(1997) American Journal of Human Genetics, 60 p.1068-1078
Journal articleTranscription of human endogenous retroviral sequences related to mouse mammary tumor virus in human breast and placenta : similar pattern in most malignant and nonmalignant breast tissues
H Yin, P Medstrand, M L Andersson, Åke Borg, Håkan Olsson, et al.
(1997) AIDS Research and Human Retroviruses, 13 p.507-516
Journal articleDistinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations
M Tirkkonen, O Johannsson, B A Agnarsson, Håkan Olsson, S Ingvarsson, et al.
(1997) Cancer Research, 57 p.7-1222
Journal articleAn estrogen receptor mutant with strong hormone-independent activity from a metastatic breast cancer
Q X Zhang, A Borg, D M Wolf, S Oesterreich, S A Fuqua
(1997) Cancer Research, 57 p.9-1244
Journal articleTumour biological features of BRCA1-induced breast and ovarian cancer
O T Jóhannsson, I Idvall, C Anderson, Åke Borg, R B Barkardóttir, et al.
(1997) European Journal of Cancer, 33 p.362-371
Journal articleIdentification of TP53 gene mutations in uterine corpus cancer with short follow-up
Anjila Koul, Åke Borg, Tanja Pejovic, Pär-Ola Bendahl, Thomas Högberg, et al.
(1997) Gynecologic Oncology, 67 p.295-302
Journal articleReduced testosterone, 17 beta-oestradiol and sexual hormone binding globulin, and increased insulin-like growth factor-1 concentrations, in healthy nulligravid women aged 19-25 years who were first and/or second degree relatives to breast cancer patients
Helena Jernström, Håkan Olsson, Åke Borg
(1997) European Journal of Cancer Prevention, 6 p.330-340
Journal articleActivated cell cycle checkpoints in epirubicin-treated breast cancer cells studied by BrdUrd-flow cytometry
Ingrid Hedenfalk, Bo Baldetorp, Åke Borg, Stina Oredsson
(1997) Cytometry, 29 p.321-327
Journal articleTumor Biological Features of BRCA1-Induced Breast Cancer
Oscar Thor Johannsson, Ingrid Idvall, C. Andersson, Åke Borg, R.B. Barkardóttir, et al.
(1997) European Journal of Cancer, 33 p.362-371
Journal articleBRCA1 mutations and survival in women with ovarian cancer [1] (multiple letters)
S. A. Cannistra, S. E. Whittmore, R. D. Burk, B. Modan, Oskar Thor Johannsson, et al.
(1997) New England Journal of Medicine, 336 p.1254-1257
Journal article (letter)Allelic loss at chromosome 13q12-q13 is associated with poor prognosis in familial and sporadic breast cancer
J van den Berg, O Johannsson, S Håkansson, Håkan Olsson, Åke Borg
(1996) British Journal of Cancer, 74 p.1615-1619
Journal articleMultiple splicing variants of the estrogen receptor are present in individual human breast tumors
Q X Zhang, S G Hilsenbeck, S A Fuqua, A Borg
(1996) Journal of Steroid Biochemistry and Molecular Biology, 59 p.60-251
Journal articleA novel p53 germline alteration identified in a late onset breast cancer kindred
X F Sun, O Johannsson, S Håkansson, G Sellberg, B Nordenskjöld, et al.
(1996) Oncogene, 13 p.11-407
Journal articleChromosome aberrations in prophylactic mastectomies from women belonging to breast cancer families
C Petersson, N Pandis, F Mertens, A Adeyinka, C Ingvar, et al.
(1996) Genes, Chromosomes and Cancer, 16 p.185-188
Journal articleNovel germline p16 mutation in familial malignant melanoma in southern Sweden
Åke Borg, U Johannsson, O Johannsson, Sara Hakansson, J Westerdahl, et al.
(1996) Cancer Research, 56 p.500-2497
Journal articleUrokinase plasminogen activator, a strong independent prognostic factor in breast cancer, analysed in steroid receptor cytosols with a luminometric immunoassay
Mårten Fernö, Pär-Ola Bendahl, Åke Borg, J Brundell, L Hirschberg, et al.
(1996) European Journal of Cancer, 32a p.793-801
Journal articleDetection of Germline BRCA1 Mutations in Breast Cancer Patients by Quantitative Messenger RNA in situ Hybridization
Tommi Kainu, Juha Kononen, Oskar Johansson, Håkan Olsson, Åke Borg, et al.
(1996) Cancer Research , p.2912-2915
Journal articleGenetic predisposition to breast cancer
Håkan Olsson, Åke Borg
(1996) Acta oncologica (Stockholm, Sweden), 35 p.1-8
Journal articleFounding BRCA1 Mutations in Hereditary Breast and Ovarian Cancer in Southern Sweden
Oscar Thor Johannsson, E.A. Ostermeyer, S. Hakansson, L.S. Friedman, U. Johansson, et al.
(1996) American Journal of Human Genetics, 58 p.441-450
Journal articleTP53 mutations and breast cancer prognosis : particularly poor survival rates for cases with mutations in the zinc-binding domains
A L Børresen, T I Andersen, Jórunn Erla Eyfjörd, R S Cornelis, Steinunn Thorlacius, et al.
(1995) Genes, Chromosomes and Cancer, 14 p.5-71
Journal articleA Collaborative Survey of 80 Mutations in the BRCA1 Breast and Ovarian Cancer Susceptibility Gene : Implications for Presymptomatic Testing and Screening
Donna Shattuck Eidens, Melody Mcclure, Jacques Simard, Fernand Labrie, Steve Narod, et al.
(1995) JAMA: The Journal of the American Medical Association, 273 p.535-541
Journal articleRecurrence-free survival in breast cancer improved by adjuvant tamoxifen--especially for progesterone receptor positive tumors with a high proliferation
Mårten Fernö, Bo Baldetorp, Pär-Ola Bendahl, Åke Borg, Sven-Börje Ewers, et al.
(1995) Breast Cancer Research and Treatment, 36 p.23-34
Journal articleBreast imaging : A comparison of digital luminescence radiographs displayed on TV-monitor and film-screen mammography
O. Jarlman, A. Borg, M. Braw, M. Kehler, K. Lyttkens, et al.
(1994) Cancer Detection and Prevention, 18 p.375-381
Journal articleHigh frequency of allelic imbalance at the BRCA1 region on chromosome 17q in both familial and sporadic ductal breast carcinomas
A Borg, Q X Zhang, O Johannsson, H Olsson
(1994) Journal of the National Cancer Institute, 86 p.4-792
Journal articleCathepsin D, both a prognostic factor and a predictive factor for the effect of adjuvant tamoxifen in breast cancer. South Sweden Breast Cancer Group
Mårten Fernö, Bo Baldetorp, Åke Borg, J P Brouillet, Håkan Olsson, et al.
(1994) European Journal of Cancer, 30a p.2042-2048
Journal articleERBB2 amplification is associated with tamoxifen resistance in steroid-receptor positive breast cancer
Åke Borg, Bo Baldetorp, Mårten Fernö, Dick Killander, Håkan Olsson, et al.
(1994) Cancer Letters, 81 p.137-144
Journal articleAn exon 5 deletion variant of the estrogen receptor frequently coexpressed with wild-type estrogen receptor in human breast cancer
Q X Zhang, A Borg, S A Fuqua
(1993) Cancer Research, 53 p.4-5882
Journal articleThe Retinoblastoma Gene in Breast Cancer : Allele Loss Is Not Correlated with Loss of Gene Protein Expression
Ake Borg, Qiu Xia Zhang, Per Aim, Håkan Olsson, Gunilla Sellberg
(1992) Cancer Research, 52 p.2991-2994
Journal articleChromosome I alterations in breast cancer : Allelic loss on Ip and Iq Is related to lymphogenic metastases and poor prognosis
Åke Borg, Qiu‐Xia Zhang, Håkan Olsson, Eva Wenngren
(1992) Genes, Chromosomes and Cancer, 5 p.311-320
Journal articlec-myc amplification is an independent prognostic factor in postmenopausal breast cancer
Åke Borg, Bo Baldetorp, Mårten Fernö, Håkan Olsson, Helgi Sigurdsson
(1992) International Journal of Cancer, 51 p.687-691
Journal articlePrognostic significance of flow cytometric DNA analysis and estrogen receptor content in breast carcinomas--a 10 year survival study
Sven-Börje Ewers, R Attewell, Bo Baldetorp, Åke Borg, Mårten Fernö, et al.
(1992) Breast Cancer Research and Treatment, 24 p.115-126
Journal articlePrognostic potential of flow cytometric S-phase and ploidy prospectively determined in primary breast carcinomas
Sven-Börje Ewers, Robyn Attewell, Bo Baldetorp, Åke Borg, Eva Långström-Einarsson, et al.
(1992) Breast Cancer Research and Treatment, 20 p.93-108
Journal articleFlow cytometric DNA index and S-phase fraction in breast cancer in relation to other prognostic variables and to clinical outcome
Mårten Fernö, Bo Baldetorp, Åke Borg, Håkan Olsson, Helgi Sigurdsson, et al.
(1992) Acta Oncologica, 31 p.157-165
Journal articleFlow cytometry DNA analysis and prediction of loco-regional recurrences after mastectomy in breast cancer
Sven-Börje Ewers, Robyn Attewell, Bo Baldetorp, Åke Borg, Mårten Fernö, et al.
(1992) Acta Oncologica, 31 p.733-740
Journal articleEarly oral contraceptive use and premenopausal breast cancer--a review of studies performed in southern Sweden.
H. Olsson, A. Borg, M. Fernö, T. R. Möller, J. Ranstam
(1991) Cancer Detection and Prevention, 15 p.265-271
Journal articleHER-2/neu and INT2 proto-oncogene amplification in malignant breast tumors in relation to reproductive factors and exposure to exogenous hormones
Håkan Olsson, Åke Borg, Mårten Fernö, Jonas Ranstam, Helgi Sigurdsson
(1991) Journal of the National Cancer Institute, 83 p.1483-1487
Journal articleDNA ploidy assessment of breast milk (colostrum) in primiparous women of different ages
Håkan Olsson, Bengt Lindahl, Bo Baldetorp, Åke Borg, Mårten Fernö, et al.
(1991) Breast Disease, 4 p.219-222
Journal articleAssociation of int2/hst1 coamplification in primary breast cancer with hormone-dependent phenotype and poor prognosis
A. Borg, H. Sigurdsson, G. M. Clark, M. Ferno, S. A.W. Fuqua, et al.
(1991) British Journal of Cancer, 63 p.136-142
Journal articleERBB2 amplification in breast cancer with a high rate of proliferation
Åke Borg, Bo Baldetorp, Mårten Fernö, Dick Killander, Håkan Olsson, et al.
(1991) Oncogene, 6 p.137-143
Journal articleHER-2/neu amplification predicts poor survival in node-positive breast cancer
A Borg, A K Tandon, H Sigurdsson, G M Clark, M Fernö, et al.
(1990) Cancer Research, 50 p.7-4332
Journal articleRelationship of progesterone-receptor positivity in malignant breast tumors to reproductive status of women at tumor initiation - results from patients with possible radiation-induced tumors
H. Olsson, H. Sigurdsson, Å Borg, M. Fernö
(1990) Journal of the National Cancer Institute, 82 p.529-531
Journal articleEstrogen and progesterone receptor analyses in more than 4000 human breast cancer samples : A study with special reference to age at diagnosis and stability of analyses
M. Fernö, Å Borg, U. Johansson, A. Norgren, H. Olsson, et al.
(1990) Acta Oncologica, 29 p.129-135
Journal articlePrognostic indicators in node-negative breast cancer (Reply)
H. Sigurdsson, B. Baldetorp, A. Borg, M. Ferno, D. Killander, et al.
(1990) New England Journal of Medicine, 323 p.1349-1350
Journal article (letter)Indicators of prognosis in node-negative breast cancer
H Sigurdsson, Bo Baldetorp, Åke Borg, M Dalberg, Mårten Fernö, et al.
(1990) New England Journal of Medicine, 322 p.1045-1053
Journal articleFlow cytometry in primary breast cancer: improving the prognostic value of the fraction of cells in the S-phase by optimal categorisation of cut-off levels
H Sigurdsson, Bo Baldetorp, Åke Borg, M Dalberg, Mårten Fernö, et al.
(1990) British Journal of Cancer, 62 p.786-790
Journal articleHER2/neu amplification and comedo type breast carcinoma
A Borg, F Linell, I Idvall, S Johansson, H Sigurdsson, et al.
(1989) The Lancet, 1 p.9-1268
Journal article (letter)Early oral contraceptive use as a prognostic factor in breast cancer
H. Olsson, T. R. Moller, J. Ranstam, A. Borg, M. Ferno
(1988) Anticancer research, 8 p.29-32
Journal articlePermanent alterations induced in plasma prolactin and estrogen receptor concentration in benign and malignant tissue of women who started oral contraceptive use at an early age
H. Olsson, B. Lindahl, J. Ranstam, A. Borg, M. Ferno, et al.
(1987) Anticancer research, 7 p.853-856
Journal articleA biological marker, strongly associated with early oral contraceptive use, for the selection of a high risk group for premenopausal breast cancer
H. Olsson, Å Borg, S. B. Ewers, M. Fernö, T. Möller, et al.
(1986) Medical Oncology and Tumor Pharmacotherapy, 3 p.77-81
Journal articleCorrelation between estradiol-17 beta and progesterone cytosol receptor concentration, histologic differentiation and 3H-thymidine incorporation in endometrial carcinoma
B Lindahl, P Alm, A Borg, M Fernö, H Grundsell, et al.
(1982) Anticancer research, 2 p.7-203
Journal article