The Sweden Cancerome Analysis Network - Breast (SCAN-B) Initiative: a large-scale multicenter infrastructure towards implementation of breast cancer genomic analyses in the clinical routine.

Summary, in English

Breast cancer exhibits significant molecular, pathological, and clinical heterogeneity. Current clinicopathological evaluation is imperfect for predicting outcome, which results in overtreatment for many patients, and for others, leads to death from recurrent disease. Therefore, additional criteria are needed to better personalize care and maximize treatment effectiveness and survival.

• Author: Lao Saal; Johan Vallon-Christersson; Jari Häkkinen; Cecilia Hegardt; Dorthe Grabau; Christof Winter; Christian Brueffer; Man-Hung Eric Tang; Christel Reuterswärd; Ralph Schulz; Anna K Karlsson; Anna Ehinger; Janne Malina; Jonas Manjer; Martin Malmberg; Christer Larsson; Lisa Rydén; Niklas Loman; Åke Borg
• Department/s: Breast Cancer Surgery; Breastcancer-genetics; BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation; Surgery (Lund); Tumor microenvironment; Surgery; Division of Translational Cancer Research; EpiHealth: Epidemiology for Health
• Publishing year: 2015
• Language: English
• Publication/Series: Genome Medicine
• Volume: 7
• Issue: 1
• Full text: - 977 kB; Download statistics
• Links: http://www.ncbi.nlm.nih.gov/pubmed/25722745?dopt=Abstract; http://dx.doi.org/10.1186/s13073-015-0131-9
• Document type: Journal article
• Publisher: BioMed Central (BMC)
• Topic: Surgery; Cancer and Oncology
• Status: Published
• Project: RNA sequencing for molecular diagnostics in breast cancer; Breast Cancer Surgery; Sweden Cancerome Analysis Network - Breast (SCAN-B): a large-scale multicenter infrastructure towards implementation of breast cancer genomic analyses in the clinical routine
• Research group: Breast Cancer Surgery; Surgery
• ISBN/ISSN/Other: ISSN: 1756-994X