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Kristian Pietras

Kristian Pietras

Research team manager

Kristian Pietras

Roadmap to the study of gene and protein phylogeny and evolution—A practical guide

Author

  • Florian Jacques
  • Paulina Bolivar
  • Kristian Pietras
  • Emma U. Hammarlund

Summary, in English

Developments in sequencing technologies and the sequencing of an ever-increasing number of genomes have revolutionised studies of biodiversity and organismal evolution. This accumulation of data has been paralleled by the creation of numerous public biological databases through which the scientific community can mine the sequences and annotations of genomes, transcriptomes, and proteomes of multiple species. However, to find the appropriate databases and bioinformatic tools for respective inquiries and aims can be challenging. Here, we present a compilation of DNA and protein databases, as well as bioinformatic tools for phylogenetic reconstruction and a wide range of studies on molecular evolution. We provide a protocol for information extraction from biological databases and simple phylogenetic reconstruction using probabilistic and distance methods, facilitating the study of biodiversity and evolution at the molecular level for the broad scientific community.

Department/s

  • Molecular Evolution
  • LUCC: Lund University Cancer Centre
  • Experimental oncology
  • Division of Translational Cancer Research
  • EpiHealth: Epidemiology for Health
  • StemTherapy: National Initiative on Stem Cells for Regenerative Therapy

Publishing year

2023

Language

English

Publication/Series

PLoS ONE

Volume

18

Issue

2

Document type

Journal article

Publisher

Public Library of Science (PLoS)

Topic

  • Bioinformatics and Systems Biology
  • Other Medical Sciences not elsewhere specified

Status

Published

Research group

  • Molecular Evolution
  • Experimental oncology

ISBN/ISSN/Other

  • ISSN: 1932-6203