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Carl Borrebaeck

Carl Borrebaeck

Professor

Carl Borrebaeck

An artificial intelligence-powered, patient-centric digital tool for self-management of chronic pain : a prospective, multicenter clinical trial

Author

  • Antje M. Barreveld
  • Maria L. Rosén Klement
  • Sophia Cheung
  • Ulrika Axelsson
  • Jade I. Basem
  • Anika S. Reddy
  • Carl A.K. Borrebaeck
  • Neel Mehta

Summary, in English

Objective: To investigate how a behavioral health, artificial intelligence (AI)-powered, digital self-management tool affects the daily functions in adults with chronic back and neck pain. Design: Eligible subjects were enrolled in a 12-week prospective, multicenter, single-arm, open-label study and instructed to use the digital coach daily. Primary outcome was a change in Patient-Reported Outcomes Measurement Information Systems (PROMIS) scores for pain interference. Secondary outcomes were changes in PROMIS physical function, anxiety, depression, pain intensity scores and pain catastrophizing scale (PCS) scores. Methods: Subjects logged daily activities, using PainDrainerTM, and data analyzed by the AI engine. Questionnaire and web-based data were collected at 6 and 12 weeks and compared to subjects' baseline. Results: Subjects completed the 6- (n = 41) and 12-week (n = 34) questionnaires. A statistically significant Minimal Important Difference (MID) for pain interference was demonstrated in 57.5% of the subjects. Similarly, MID for physical function was demonstrated in 72.5% of the subjects. A pre- to post-intervention improvement in depression score was also statistically significant, observed in 100% of subjects, as was the improvement in anxiety scores, evident in 81.3% of the subjects. PCS mean scores was also significantly decreased at 12 weeks. Conclusion: Chronic pain self-management, using an AI-powered, digital coach anchored in behavioral health principles significantly improved subjects' pain interference, physical function, depression, anxiety, and pain catastrophizing over the 12-week study period.

Department/s

  • LUCC: Lund University Cancer Centre
  • Department of Immunotechnology

Publishing year

2023-09-01

Language

English

Pages

1100-1110

Publication/Series

Pain Medicine (United States)

Volume

24

Issue

9

Document type

Journal article

Publisher

Oxford University Press

Topic

  • Other Health Sciences
  • Other Medical Sciences not elsewhere specified

Keywords

  • ACT
  • chronic pain
  • digital tool
  • patient-centric
  • self-management

Status

Published

ISBN/ISSN/Other

  • ISSN: 1526-2375