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Quantitative SPECT by attenuation correction of the projection set using transmission data: evaluation of a method

  • Helén Almquist
  • John Palmer
  • Michael Ljungberg
  • Per Wollmer
  • Sven-Erik Strand
  • Björn Jonson
Publishing year: 1990
Language: English
Pages: 587-594
Publication/Series: European Journal Of Nuclear Medicine
Volume: 16
Issue: 8-10
Document type: Journal article
Publisher: Springer

Abstract english

A method for measuring attenuation coefficients in single-photon emission tomography (SPECT) is described and evaluated, together with a method for attenuation correction using these measured attenuation coefficients. Build-up, caused by scattered photons, is corrected for by a simple substitution in the algorithms. Transmission studies are performed with a 99mTc- or 57Co flood source, and emission phantom studies with 99mTc line sources. The method is evaluated with variable but well-defined phantoms. The result is accurate attenuation coefficients for different densities, dimensions and geometries, and an accuracy of corrected emission activities of better than +/- 10% in most cases. The present limitations of the method for attenuation correction are discussed.


  • Radiology, Nuclear Medicine and Medical Imaging
  • Attenuation correction
  • Build-up
  • Quantitative SPECT
  • Transmission measurement


  • Clinical Physiology, Malmö
  • ISSN: 1432-105X
Sven-Erik Strand
E-mail: sven-erik [dot] strand [at] med [dot] lu [dot] se

Project manager

Systemic Radiation Therapy Group


Professor emeritus

Medical Radiation Physics, Lund