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Early posttraumatic pulmonary platelet trapping and its potentiation by oral pretreatment with alcohol

  • Johan Thörne
  • Sten Blomquist
  • Olle Elmér
  • Bo-Anders Jönsson
  • Sten Lindahl
  • Sven-Erik Strand
Publishing year: 1986
Language: English
Pages: 216-220
Publication/Series: American Journal of Surgery
Volume: 151
Issue: 2
Document type: Journal article
Publisher: Elsevier

Abstract english

Soft tissue trauma is associated with platelet aggregation and sequestration in the lungs. This is believed to be an early step in the later development of adult respiratory distress syndrome. In the present experiment using a new method for in vivo dynamic studies of platelet sequestration, we wanted to evaluate the effect of soft tissue trauma on pulmonary platelet trapping in pigs and the influence of acute alcohol intoxication. The results show that significant pulmonary platelet trapping is registered within minutes of trauma and that alcohol significantly increases platelet sequestration in the lungs. This indicates an increased risk for posttraumatic pulmonary problems in alcohol-intoxicated trauma victims


  • Surgery


  • ISSN: 1879-1883
Sven-Erik Strand
E-mail: sven-erik [dot] strand [at] med [dot] lu [dot] se

Project manager

Systemic Radiation Therapy Group


Professor emeritus

Medical Radiation Physics, Lund