Menu

Javascript is not activated in your browser. This website needs javascript activated to work properly.
You are here

Antioxidant Effects of Secondary Metabolites from Geranium psilostemon

Author:
  • Didem Sohretoglu
  • Suna Atasayar Sabuncuoglu
  • M. Koray Sakar
  • Hilal Ozgunes
  • Olov Sterner
Publishing year: 2010
Language: English
Pages: 899-902
Publication/Series: Natural Product Communications
Volume: 5
Issue: 6
Document type: Journal article
Publisher: Natural Products Inc

Abstract english

An investigation was made of the effects on endogenous antioxidant enzyme activities and H2O2-induced lipid peroxidation inhibition in human red blood cells of the crude MeOH extract and its EtOAc, n-BuOH, and H2O sub-extracts obtained from aerial parts of Geranium psilostemon Ledeb., as well as compounds isolated from the most active EtOAc extract. Gallic acid (1), methyl gallate (2), pusilagin (3), 1,3,6-tri-O-galloyl-beta-glucopyranoside (4), 1,2,3,4,6-penta-O-galloyl-beta-glucopyranoside (5), kaempferol (6), quercetin (7), kaempferol 7-O-alpha-rhamnopyranoside (8), and quercetin 7-O-alpha-rhamnopyranoside (9) were isolated from the aerial parts of the title plant, and their structures identified from spectroscopic (UV, 1D- and 2D- NMR) and spectrometric (TOF-MS) data. All extracts and isolated compounds inhibited H2O2-induced lipid peroxidation and also enhanced the activity of superoxide dismutase (SOD) and catalase (CAT).

Keywords

  • Organic Chemistry
  • pentagalloyl glucose
  • trigalloyl glucose
  • SOD
  • CAT
  • antioxidant
  • Geranium
  • Geraniaceae

Other

Published
  • ISSN: 1934-578X
Olov Sterner
E-mail: olov [dot] sterner [at] science [dot] lu [dot] se

Dean

Faculty of Science

+46 46 222 82 13

+46 70 530 66 49

B127

Sölvegatan 27, Lund

39

Professor

Centre for Analysis and Synthesis

+46 46 222 82 13

1