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Spasmolytic flavonols from Artemisia abrotanum

Author:
  • Ola Bergendorff
  • Olov Sterner
Publishing year: 1995
Language: English
Pages: 370-371
Publication/Series: Planta Medica
Volume: 61
Issue: 4
Document type: Journal article
Publisher: Georg Thieme Verlag

Abstract english

Four flavonols with spasmolytic activity have been isolated from a methanol extract of Artemisia abrotanum L. (Asteraceae), as the principles primarily responsible for the smooth muscle relaxing activity of this plant. The flavonols show a dose-dependent relaxing effect on the carbacholine-induced contraction of guinea-pig trachea, the EC50 values for compounds 1-3 are 20-30 mumol/l while compound 4 is less active.

Keywords

  • Dermatology and Venereal Diseases

Other

Published
  • ISSN: 0032-0943
Olov Sterner
E-mail: olov [dot] sterner [at] science [dot] lu [dot] se

Dean

Faculty of Science

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Professor

Centre for Analysis and Synthesis

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