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Neosordarin and hydroxysordarin, two new antifungal agents from Sordaria araneosa

Author:
  • P Davoli
  • G Engel
  • A Werle
  • Olov Sterner
  • T Anke
Publishing year: 2002
Language: English
Pages: 377-382
Publication/Series: Journal of Antibiotics
Volume: 55
Issue: 4
Document type: Journal article
Publisher: Japan Antibiotics Research Association

Abstract english

Two novel antifungal agents belonging to the sordarin family have been isolated from fermentations of Sordaria araneosa by bioassay-guided purification and their structures elucidated by NMR techniques. Neosordarin (1) is closely related to the recently discovered hypoxysordarin (2), with only small differences on the aliphatic side chain acylating the hydroxyl in the 3'-position of the sordarose moiety. Hydroxysordarin (3) closely resembles sordarin (4), the only slight difference being the replacement of sordarose with altrose as the sugar unit.

Keywords

  • Organic Chemistry

Other

Published
  • ISSN: 0021-8820
Olov Sterner
E-mail: olov [dot] sterner [at] science [dot] lu [dot] se

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Faculty of Science

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