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Antimicrobial activity of metabolites from mycelial cultures of Chilean Basidiomycetes

  • Pedro Aqueveque
  • Jose Becerra
  • Gotz Palfner
  • Mario Silva
  • Julio Alarcon
  • Timm Anke
  • Olov Sterner
Publishing year: 2006
Language: English
Pages: 1059-1060
Publication/Series: Journal of the Chilean Chemical Society
Volume: 51
Issue: 4
Document type: Journal article
Publisher: Sociedad Chilena de Química

Abstract english

We reported seven compounds isolated from mycelial cultures of Chilean Basidiomycetes. The compound structures were elucidated by spectroscopic methods. Two polyacetylenes were isolated from Gymnopilus spectabilis: hepta-4,6-diyn-3-ol (1) and 7-chloro-hepta-4,6-diyn-3 ol (2). We isolated the aromatic compounds p-anisaldehyde (3) and 3-chloro-p-anisaldehyde (4) from Hypholoma capnoides. H. fasciculare produced the compounds (3), (4), 3,5-dichloro-4-metoxi-benzyl alcohol (5) and the sesquiterpen naematolon (6). Finally, H. sublateritium produced (5) and another sesquiterpen, marasmal (7). The compounds (1), (2), (5), and (7) showed biological activity against the tested model microorganism.


  • Organic Chemistry
  • Chilean fungi
  • biological activity
  • basidiomycetes


  • ISSN: 0717-9707
Olov Sterner
E-mail: olov [dot] sterner [at] chem [dot] lu [dot] se


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