The himanimides, new bioactive compounds from Serpula himantoides (Fr.)Karst.
- Centre for Analysis and Synthesis
Publishing year: 2002
Publication/Series: Zeitschrift fuer Naturforschung. Section C: A Journal of Biosciences
Document type: Journal article
Publisher: Verlag der Zeitschrift für Naturforschung
In a screening of basidiomycete cultures from Chile for the production of antibiotics we identified a Serpula himantoides strain as a producer of metabolites inhibiting the growth of bacteria and fungi. Bioactivity guided purification resulted in the isolation of four new antibiotics. Their structures were elucidated by spectroscopic methods. All four compounds are succinimide and maleimide derivatives, of which two are N-hydroxylated.
- Organic Chemistry
- ISSN: 0939-5075