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Antiamoebins, myrocin B and the basis of antifungal antibiosis in the coprophilous fungus Stilbella erythrocephala(syn. S-fimetaria)

  • N A Lehr
  • A Meffert
  • L Antelo
  • Olov Sterner
  • H Anke
  • R Weber
Publishing year: 2006
Language: English
Pages: 105-112
Publication/Series: FEMS Microbiology Ecology
Volume: 55
Issue: 1
Document type: Journal article
Publisher: Elsevier

Abstract english

Antiamoebins I, III and XVI as well as several others in minor amounts were produced by four strains of the coprophilous fungus Stilbella erythrocephala (syn. S. fimetaria) in its natural substrate and in liquid culture. The total antiamoebin concentration in dung was 126-624 mu g g(-1) fresh weight, with minimum inhibitory concentrations against most other coprophilous fungi being at or below 100 mu g mL(-1). Myrocin B, not previously described from S. erythrocephala, was also produced, but only at low, nonfungicidal levels (<5.3 mu g g(-1)). No other antifungal substances were detected. It is concluded that antiamoebins are responsible for antibiosis in dung colonized by S. erythrocephala.


  • Organic Chemistry
  • coprophilous fungi
  • antibiosis
  • myrocin B
  • antiamoebins
  • Stilbella erythrocephala
  • Stilbella fimetaria


  • ISSN: 1574-6941
Olov Sterner
E-mail: olov [dot] sterner [at] science [dot] lu [dot] se


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