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Prenylated isoflavanone from the roots of Erythrina sigmoidea

Author:
  • Augustin E Nkengfack
  • Timothee W Vouffo
  • Z T Fomum
  • Michele Meyer
  • Ola Bergendorff
  • Olov Sterner
Publishing year: 1994
Language: English
Pages: 1047-1051
Publication/Series: Phytochemistry
Volume: 36
Issue: 4
Document type: Journal article
Publisher: Elsevier

Abstract english

A novel prenylated isoflavanone, sigmoidin I, has been isolated from the roots of Erythrina sigmoidea, in addition to the known isoflavones, corylin and neobavaisoflavone and the known pterocarpan, phaseollidin. Its structure was established as 7,4'-dihydroxy-3'-methoxy-5'-(3-methylbut-2-enyl) isoflavanone by means of spectroscopic analyses and chemical transformations. Neobavaisoflavone displayed antifungal potency in vitro with minimum inhibitory concentrations against Aspergillus fumigatus and Cryptococcus neoformans, of 50 mg ml-1.

Keywords

  • Dermatology and Venereal Diseases
  • Erythrina sigmoidea
  • Leguminosae
  • roots
  • sigmoidin I
  • neobavaisoflavone
  • corylin
  • phaseollidin
  • antifungal activity

Other

Published
  • ISSN: 0031-9422
Olov Sterner
E-mail: olov [dot] sterner [at] science [dot] lu [dot] se

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