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Håkan Axelson

Håkan Axelson

Research team manager

Håkan Axelson

The miR(21/10b) ratio as a prognostic marker in clear cell renal cell carcinoma.

Author

  • Helena Fritz
  • David Lindgren
  • Börje Ljungberg
  • Håkan Axelson
  • Björn Dahlbäck

Summary, in English

Clear cell renal cell carcinoma (ccRCC) is the most common type of cancer in the adult kidney, and the prognosis of metastatic ccRCC remains poor with high mortality. In ccRCC, microRNAs (miRs) differentially expressed in tumour tissue have been identified and have been proposed to predict prognosis. The purpose of this study was to evaluate candidate miR markers identified from analysis of The Cancer Genome Atlas (TCGA) datasets in a large RCC cohort and to elucidate whether a ratio of miRs provided additional prognostic information.

Department/s

  • Clinical Chemistry, Malmö
  • Division of Translational Cancer Research
  • BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation

Publishing year

2014

Language

English

Pages

1758-1765

Publication/Series

European Journal of Cancer

Volume

50

Issue

10

Document type

Journal article

Publisher

Elsevier

Topic

  • Cancer and Oncology

Status

Published

Research group

  • Clinical Chemistry, Malmö

ISBN/ISSN/Other

  • ISSN: 1879-0852