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The miR(21/10b) ratio as a prognostic marker in clear cell renal cell carcinoma.

Author:
  • Helena Fritz
  • David Lindgren
  • Börje Ljungberg
  • Håkan Axelson
  • Björn Dahlbäck
Publishing year: 2014
Language: English
Pages: 1758-1765
Publication/Series: European Journal of Cancer
Volume: 50
Issue: 10
Document type: Journal article
Publisher: IFAC & Elsevier Ltd.

Abstract english

Clear cell renal cell carcinoma (ccRCC) is the most common type of cancer in the adult kidney, and the prognosis of metastatic ccRCC remains poor with high mortality. In ccRCC, microRNAs (miRs) differentially expressed in tumour tissue have been identified and have been proposed to predict prognosis. The purpose of this study was to evaluate candidate miR markers identified from analysis of The Cancer Genome Atlas (TCGA) datasets in a large RCC cohort and to elucidate whether a ratio of miRs provided additional prognostic information.

Keywords

  • Cancer and Oncology

Other

Published
  • Clinical Chemistry, Malmö
  • ISSN: 1879-0852
Håkan Axelson
E-mail: hakan [dot] axelson [at] med [dot] lu [dot] se

Professor

Division of Translational Cancer Research

+46 46 222 64 34

MV 404 A31A2

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