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Håkan Axelson

Håkan Axelson

Research team manager

Håkan Axelson

The Notch and TGF-beta Signaling Pathways Contribute to the Aggressiveness of Clear Cell Renal Cell Carcinoma.

Author

  • Jonas Sjölund
  • Anna-Karin Boström
  • David Lindgren
  • Sugata Manna
  • Aristidis Moustakas
  • Börje Ljungberg
  • Martin Johansson
  • Erik Fredlund
  • Håkan Axelson

Summary, in English

Despite recent progress, therapy for metastatic clear cell renal cell carcinoma (CCRCC) is still inadequate. Dysregulated Notch signaling in CCRCC contributes to tumor growth, but the full spectrum of downstream processes regulated by Notch in this tumor form is unknown.

Department/s

  • Department of Translational Medicine
  • Breastcancer-genetics
  • BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation

Publishing year

2011

Language

English

Publication/Series

PLoS ONE

Volume

6

Issue

8

Document type

Journal article

Publisher

Public Library of Science (PLoS)

Topic

  • Cancer and Oncology

Status

Published

ISBN/ISSN/Other

  • ISSN: 1932-6203