The Notch and TGF-beta Signaling Pathways Contribute to the Aggressiveness of Clear Cell Renal Cell Carcinoma.
- Department of Translational Medicine
- Oncology and Pathology, MV
Publishing year: 2011
Publication/Series: PLoS ONE
Document type: Journal article
Publisher: Public Library of Science
Despite recent progress, therapy for metastatic clear cell renal cell carcinoma (CCRCC) is still inadequate. Dysregulated Notch signaling in CCRCC contributes to tumor growth, but the full spectrum of downstream processes regulated by Notch in this tumor form is unknown.
- Cancer and Oncology
- ISSN: 1932-6203