Carl Borrebaeck
Professor
Precision diagnostics : moving towards protein biomarker signatures of clinical utility in cancer
Author
Summary, in English
Interest in precision diagnostics has been fuelled by the concept that early detection of cancer would benefit patients; that is, if detected early, more tumours should be resectable and treatment more efficacious. Serum contains massive amounts of potentially diagnostic information, and affinity proteomics has risen as an accurate approach to decipher this, to generate actionable information that should result in more precise and evidence-based options to manage cancer. To achieve this, we need to move from single to multiplex biomarkers, a so-called signature, that can provide significantly increased diagnostic accuracy. This Opinion article focuses on the progress being made in identifying protein biomarker signatures of clinical utility, using blood-based proteomics.
Department/s
- Create Health
- Department of Immunotechnology
- BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
Publishing year
2017-02-03
Language
English
Pages
199-204
Publication/Series
Nature Reviews Cancer
Volume
17
Issue
3
Document type
Journal article review
Publisher
Nature Publishing Group
Topic
- Immunology in the medical area
Status
Published
ISBN/ISSN/Other
- ISSN: 1474-175X