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Carl Borrebaeck

Carl Borrebaeck

Professor

Carl Borrebaeck

Skin sensitizers differentially regulate signaling pathways in MUTZ-3 cells in relation to their individual potency.

Author

  • Ann-Sofie Albrekt
  • Henrik Johansson
  • Anna Börjesson
  • Carl Borrebaeck
  • Malin Lindstedt

Summary, in English

Due to the recent European legislations posing a ban of animal tests for safety assessment within the cosmetic industry, development of in vitro alternatives for assessment of skin sensitization is highly prioritized. To date, proposed in vitro assays are mainly based on single biomarkers, which so far have not been able to classify and stratify chemicals into subgroups, related to risk or potency.

Department/s

  • Department of Immunotechnology

Publishing year

2014

Language

English

Publication/Series

BMC Pharmacology

Volume

15

Issue

1

Document type

Journal article

Publisher

BioMed Central (BMC)

Topic

  • Immunology in the medical area

Status

Published

ISBN/ISSN/Other

  • ISSN: 1471-2210