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Progress in miniaturisation of proteon arrays - a step closer to high-density nanoarrays

Author:
  • Carl Borrebaeck
  • Christer Wingren
Publishing year: 2007
Language: English
Pages: 813-819
Publication/Series: Drug Discovery Today
Volume: 12
Issue: 19-20
Document type: Journal article review
Publisher: Elsevier

Abstract english

Protein microarrays is a technology with great promise for high-throughput proteomics. Designing high-performance protein microarrays for global proteome analysis has, however, turned out to be challenging. To this end, major efforts are under way to design novel array formats capable of harboring the tremendous range of probes required to target complex proteomes composed of more than 10 000 analytes. By adopting nanotechnology, the first generation of miniaturized nanoarrays has recently emerged, which opens up new avenues for global proteome analysis and disease proteomics. This review describes the progress and key issues in designing miniaturized protein arrays.

Keywords

  • Pharmaceutical Sciences

Other

Published
  • ISSN: 1878-5832
Carl Borrebaeck
E-mail: carl [dot] borrebaeck [at] immun [dot] lth [dot] se

Professor

Department of Immunotechnology

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