Skin sensitizers differentially regulate signaling pathways in MUTZ-3 cells in relation to their individual potency.
- Department of Immunotechnology
Publishing year: 2014
Publication/Series: BMC Pharmacology
Document type: Journal article
Publisher: BioMed Central
Due to the recent European legislations posing a ban of animal tests for safety assessment within the cosmetic industry, development of in vitro alternatives for assessment of skin sensitization is highly prioritized. To date, proposed in vitro assays are mainly based on single biomarkers, which so far have not been able to classify and stratify chemicals into subgroups, related to risk or potency.
- Immunology in the medical area
- ISSN: 2050-6511