Carl Borrebaeck
Professor
Progress in miniaturisation of proteon arrays - a step closer to high-density nanoarrays
Author
Summary, in English
Protein microarrays is a technology with great promise for high-throughput proteomics. Designing high-performance protein microarrays for global proteome analysis has, however, turned out to be challenging. To this end, major efforts are under way to design novel array formats capable of harboring the tremendous range of probes required to target complex proteomes composed of more than 10 000 analytes. By adopting nanotechnology, the first generation of miniaturized nanoarrays has recently emerged, which opens up new avenues for global proteome analysis and disease proteomics. This review describes the progress and key issues in designing miniaturized protein arrays.
Department/s
- Department of Immunotechnology
Publishing year
2007
Language
English
Pages
813-819
Publication/Series
Drug Discovery Today
Volume
12
Issue
19-20
Document type
Journal article review
Publisher
Elsevier
Topic
- Pharmaceutical Sciences
Status
Published
ISBN/ISSN/Other
- ISSN: 1878-5832