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Carl B

Carl Borrebaeck

Professor

Carl B

Progress in miniaturisation of proteon arrays - a step closer to high-density nanoarrays

Author

  • Carl Borrebaeck
  • Christer Wingren

Summary, in English

Protein microarrays is a technology with great promise for high-throughput proteomics. Designing high-performance protein microarrays for global proteome analysis has, however, turned out to be challenging. To this end, major efforts are under way to design novel array formats capable of harboring the tremendous range of probes required to target complex proteomes composed of more than 10 000 analytes. By adopting nanotechnology, the first generation of miniaturized nanoarrays has recently emerged, which opens up new avenues for global proteome analysis and disease proteomics. This review describes the progress and key issues in designing miniaturized protein arrays.

Department/s

  • Department of Immunotechnology

Publishing year

2007

Language

English

Pages

813-819

Publication/Series

Drug Discovery Today

Volume

12

Issue

19-20

Document type

Journal article review

Publisher

Elsevier

Topic

  • Pharmaceutical Sciences

Status

Published

ISBN/ISSN/Other

  • ISSN: 1878-5832