New chromosomal rearrangement, t(12;22)(p13;q12), in acute nonlymphocytic leukemia
- Division of Clinical Genetics
Publishing year: 1991
Publication/Series: Cancer Genetics and Cytogenetics1979-01-01+01:002011-01-01+01:00
Document type: Journal article
The karyotype 47,XX, + 8,t(12;22)(p13;q12) was found at diagnosis in two patients with acute nonlymphocytic leukemia (ANLL). The bone marrow morphology of both patients corresponded to the M4 subtype of the French-American-British (FAB) classification. The translocation t(12;22) has not previously been reported as the sole structural aberration in ANLL.
- Medical Genetics
- ISSN: 0165-4608