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New chromosomal rearrangement, t(12;22)(p13;q12), in acute nonlymphocytic leukemia

Author:
  • David F Callen
  • Yvonne J Hull
  • Ian R Toogood
  • Thoas Fioretos
  • Sverre Heim
  • Nils Mandahl
  • Felix Mitelman
Publishing year: 1991
Language: English
Pages: 255-258
Publication/Series: Cancer Genetics and Cytogenetics1979-01-01+01:002011-01-01+01:00
Volume: 51
Issue: 2
Document type: Journal article
Publisher: Elsevier

Abstract english

The karyotype 47,XX, + 8,t(12;22)(p13;q12) was found at diagnosis in two patients with acute nonlymphocytic leukemia (ANLL). The bone marrow morphology of both patients corresponded to the M4 subtype of the French-American-British (FAB) classification. The translocation t(12;22) has not previously been reported as the sole structural aberration in ANLL.

Keywords

  • Medical Genetics

Other

Published
  • ISSN: 0165-4608
Thoas Fioretos
E-mail: thoas.fioretos [at] med.lu.se

Principal investigator

Division of Clinical Genetics

+46 46 222 45 95

+46 70 334 33 67

BMC C13

66