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Molekylär medicin: Molekylärgenetisk metodik avslöjar mekanismerna bakom tumörutveckling

Molecular genetics methods discovering the mechanisms of neoplasm etiology
Author:
  • Thoas Fioretos
  • Pierre Åman
Publishing year: 1991
Language: Swedish
Pages: 2597-2602
Publication/Series: Läkartidningen
Volume: 88
Issue: 32-33
Document type: Journal article
Publisher: Sveriges Läkarförbund

Abstract english

The rapid advance in our understanding of cancer biology during the past decade, as exemplified by the discovery of oncogenes and tumour suppressor genes and their interactions in tumourigenesis, has revolutionized cancer research. This rapid progress has largely been due to the use of molecular genetics techniques. However, despite the wealth of available information as to the genetic basis of carcinogenesis, its clinical applicability remains limited. The review is a summary of the general principles and methods currently used to detect genetic alterations in neoplastic cells, with special emphasis on clinical applications.

Keywords

  • Medical Genetics
  • Molekylärbiologi
  • Biokemisk genetik
  • Neoplastisk celltransformation
  • Genetiska tekniker

Other

Published
  • ISSN: 0023-7205
Thoas Fioretos
E-mail: thoas.fioretos [at] med.lu.se

Principal investigator

Division of Clinical Genetics

+46 46 222 45 95

+46 70 334 33 67

BMC C13

66