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Thoas Fioretos

Thoas Fioretos

Research team manager

Thoas Fioretos

Molekylär medicin: Molekylärgenetisk metodik avslöjar mekanismerna bakom tumörutveckling

Molecular genetics methods discovering the mechanisms of neoplasm etiology

Author

  • Thoas Fioretos
  • Pierre Åman

Summary, in English

The rapid advance in our understanding of cancer biology during the past decade, as exemplified by the discovery of oncogenes and tumour suppressor genes and their interactions in tumourigenesis, has revolutionized cancer research. This rapid progress has largely been due to the use of molecular genetics techniques. However, despite the wealth of available information as to the genetic basis of carcinogenesis, its clinical applicability remains limited. The review is a summary of the general principles and methods currently used to detect genetic alterations in neoplastic cells, with special emphasis on clinical applications.

Department/s

  • Division of Clinical Genetics

Publishing year

1991

Language

Swedish

Pages

2597-2602

Publication/Series

Läkartidningen

Volume

88

Issue

32-33

Document type

Journal article

Publisher

Swedish Medical Association

Topic

  • Medical Genetics

Keywords

  • Molekylärbiologi
  • Biokemisk genetik
  • Neoplastisk celltransformation
  • Genetiska tekniker

Status

Published

ISBN/ISSN/Other

  • ISSN: 0023-7205