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Beta camera low activity tumor imaging

Author:
  • Kaj Ljunggren
  • Sven-Erik Strand
  • Crister Ceberg
  • Hans Sjöholm
  • Dan Elmqvist
  • Arne Brun
  • Leif Salford
Publishing year: 1993
Language: English
Pages: 869-872
Publication/Series: Acta Oncologica
Volume: 32
Issue: 7-8
Document type: Journal article
Publisher: Taylor & Francis

Abstract english

A new technique, the beta camera, to complement film autoradiography, with fast quantitative imaging of beta particle-emitting radionuclides has been developed. It consists of a thin plastic scintillator and a light-sensitive microchannel plate detector. The thin tissue sample is mounted on the scintillator. Our first system had a high background and a moderate spatial resolution of 900 microns. We now report an improved system with a photomultiplier tube mounted on the scintillator of the microchannel plate detector. Only events registered by both detectors are accepted. A fast coincidence unit processes the signals, and if a time overlap exists, an event is generated in the beta camera. In the coincidence mode, images with low activity distribution of 201Tl (count rate 1 s-1) in 50 microns-thick slices of a human glioma tumor could be recorded with a spatial resolution of 500 microns.

Keywords

  • Cancer and Oncology

Other

Published
  • ISSN: 1651-226X
Sven-Erik Strand
E-mail: sven-erik.strand [at] med.lu.se

Project manager

Systemic Radiation Therapy Group

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Professor emeritus

Medical Radiation Physics, Lund

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