Inhibition of kainic acid binding to glutamate receptors by extracts of Gastrodia
- Department of Dermatology and Venereology (Lund)
- Centre for Analysis and Synthesis
Publishing year: 1995
Document type: Journal article
S-(4-hydroxybenzyl)glutathione was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata. The affinity (IC50 value) of the compound is slightly lower compared to glutamate and glutathione.
- Dermatology and Venereal Diseases
- ISSN: 0031-9422