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Laschiatrion, a new antifungal agent from a Favolaschia species (Basidiomycetes) active against human pathogens

Author:
  • T Anke
  • A Werle
  • R B Kappe
  • Olov Sterner
Publishing year: 2004
Language: English
Pages: 496-501
Publication/Series: Journal of Antibiotics
Volume: 57
Issue: 8
Document type: Journal article
Publisher: Japan Antibiotics Research Association

Abstract english

Laschiatrion (1), a new antifungal antibiotic, was isolated from fermentations of Favolaschia sp. 87129. (1) exhibits broad in vitro activity against several human pathogens while no antibacterial and cytotoxic activities could be detected. The structure was elucidated by spectroscopic techniques. As to our knowledge laschiatrion possesses a new steroid skeleton.

Keywords

  • Organic Chemistry

Other

Published
  • ISSN: 0021-8820
Olov Sterner
E-mail: olov.sterner [at] science.lu.se

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