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Two new biologically active cyclopentenones from Dasyseyphus sp A47-98

Author:
  • V Mierau
  • Olov Sterner
  • T Anke
Publishing year: 2004
Language: English
Pages: 311-315
Publication/Series: Journal of Antibiotics
Volume: 57
Issue: 5
Document type: Journal article
Publisher: Japan Antibiotics Research Association

Abstract english

Two new biological active cyclopentenones VM 4798-1a (1a) and VM 4798-1b (1b) were obtained as a 3 : 1 inseparable mixture from fermentations of Dasyscyphus sp. A47-98. The mixture of the two isomers showed cytotoxic and weak antibacterial and antifungal properties. VM 4898-1 (2-hydroxy-3,4-dimethyl-2-cyclopenten-1-one, 4), produced by another Dasyscyphus sp. showed no significant biological activity. The structures were elucidated by NMR techniques.

Keywords

  • Organic Chemistry

Other

Published
  • ISSN: 0021-8820
Olov Sterner
E-mail: olov.sterner [at] science.lu.se

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