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Mollisianitrile, a new antibiotic from Mollisia sp A59-96

Author:
  • Daniela Weber
  • Olov Sterner
  • Timm Anke
Publishing year: 2007
Language: English
Pages: 567-570
Publication/Series: Zeitschrift fuer Naturforschung. Section C: A Journal of Biosciences
Volume: 62
Issue: 7-8
Document type: Journal article
Publisher: Verlag der Zeitschrift für Naturforschung

Abstract english

Mollisianitrile (1), a new antibiotic was isolated from the fermentation broth of Mollisa sp. A59-96 together with the two known isocoumarins 2 and 3. 1 exhibited antimicrobial, cytotoxic, and phytotoxic activities. 1 contains a reactive propiolonitrile moiety which is believed to be responsible for its antibiotic activities. Upon incubation with L-cysteine the biological activity was lost.

Keywords

  • Organic Chemistry
  • antimicrobial and cytotoxic activities
  • mollisia
  • mollisianitrile

Other

Published
  • ISSN: 0939-5075
Olov Sterner
E-mail: olov.sterner [at] science.lu.se

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