Biologically active metabolites from the basidiomycete Limacella illinita (Fr.) Murr.
- Centre for Analysis and Synthesis
Publishing year: 2007
Publication/Series: Zeitschrift fuer Naturforschung. Section C: A Journal of Biosciences
Document type: Journal article
Publisher: Verlag der Zeitschrift für Naturforschung
In the course of our search for new bioactive compounds from basidiomycetes, four new compounds were isolated from fermentations of Limacella illinita. Illinitone A (1) exhibited weak phytotoxic and moderate nematicidal activities against Caenorhabditis elegans, illinitone B (2) was moderately cytotoxic, while limacellone (3) exhibited weak cytotoxic and phytotoxic activities. The muurolane sesquiterpene 4a was found to be inactive in the assays performed here. Limacellone (3), which appeared to be related with the illinitones 1 and 2, has a new C-15 carbon skeleton. It is possible that compounds 1, 2 and 3 are terpenoids/secoterpenoids, but their biosyntheses were not investigated.
- Organic Chemistry
- Limacella illinita
- ISSN: 0939-5075