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Kristian Pietras

Kristian Pietras

Research team manager

Kristian Pietras

Decoding breast cancer tissue-stroma interactions using species-specific sequencing.

Author

  • Indira V Chivukula
  • Daniel Ramsköld
  • Helena Storvall
  • Charlotte Anderberg
  • Shaobo Jin
  • Veronika Mamaeva
  • Cecilia Sahlgren
  • Kristian Pietras
  • Rickard Sandberg
  • Urban Lendahl

Summary, in English

Decoding transcriptional effects of experimental tissue-tissue or cell-cell interactions is important; for example, to better understand tumor-stroma interactions after transplantation of human cells into mouse (xenografting). Transcriptome analysis of intermixed human and mouse cells has, however, frequently relied on the need to separate the two cell populations prior to transcriptome analysis, which introduces confounding effects on gene expression.

Department/s

  • Division of Translational Cancer Research
  • BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation

Publishing year

2015

Language

English

Publication/Series

Breast Cancer Research

Volume

17

Document type

Journal article

Publisher

BioMed Central (BMC)

Topic

  • Cancer and Oncology

Status

Published

ISBN/ISSN/Other

  • ISSN: 1465-5411