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Gradient echo imaging of flowing hyperpolarized nuclei : theory and phantom studies on 129Xe dissolved in ethanol

Author:
  • Edvin Johansson
  • Jonas Svensson
  • S Månsson
  • J S Petersson
  • L E Olsson
  • K Golman
  • F Ståhlberg
Publishing year: 2002-11
Language: English
Pages: 68-75
Publication/Series: Journal of Magnetic Resonance
Volume: 159
Issue: 1
Document type: Journal article
Publisher: Elsevier

Abstract english

The influence of flip angle and flow velocity on the signal intensity achieved when imaging a hyperpolarized substance with a spoiled gradient echo sequence was investigated. The study was performed both theoretically and experimentally using hyperpolarized xenon dissolved in ethanol. Analytical expressions regarding the optimal flip angle with respect to signal and the corresponding signal level are presented and comparisons with thermally polarized substances are made. Both experimentally and theoretically, the optimal flip angle was found to increase with increasing flow velocity. Numerical calculations showed that the velocity dependence of the signal differs between the cases of hyperpolarized and thermally polarized substances.

Keywords

  • Radiology, Nuclear Medicine and Medical Imaging
  • Echo-Planar Imaging
  • Ethanol
  • Magnetic Resonance Angiography
  • Phantoms, Imaging
  • Xenon Isotopes

Other

Published
  • Medical Radiation Physics, Malmö
  • Radiology Diagnostics, Malmö
  • ISSN: 1090-7807
Freddy Ståhlberg
E-mail: freddy.stahlberg [at] med.lu.se

Professor

Medical Radiation Physics, Lund

+46 46 17 31 19

+46 70 688 31 19

32

Professor

Diagnostic Radiology, (Lund)

+46 46 17 70 30

32