Menu

Javascript is not activated in your browser. This website needs javascript activated to work properly.
You are here

Use of an enhanced gradient system for diffusion MR imaging with motion-artifact reduction

Author:
  • Sara Brockstedt
  • C Thomsen
  • Ronnie Wirestam
  • J De Poorter
  • C De Wagter
  • Leif Salford
  • Stig Holtås
  • Freddy Ståhlberg
Publishing year: 1995
Language: English
Pages: 662-670
Publication/Series: Acta Radiologica
Volume: 36
Issue: 6
Document type: Journal article
Publisher: John Wiley & Sons

Abstract english

PURPOSE: A spin-echo diffusion-sensitized pulse sequence using high gradients (23 mT/m) is introduced. MATERIAL AND METHODS: In order to minimize motion artefacts, velocity-compensating gradients, ECG-triggering and post-processing with phase correction and raw data averaging using navigator echoes was performed. The in vitro ratio of diffusion coefficients for water and acetone was determined and the water self-diffusion coefficient at different temperatures was evaluated. The pulse sequence was tested in 7 healthy volunteers and in 2 tumour patients with astrocytomas of grades I-II and III-IV. Both single-slice and multi-slice techniques were used. RESULTS: The incorporation of phase correction clearly improved the quality of both diffusion-encoded images and the calculated diffusion maps. Mean values of the diffusion coefficients in vivo were for CSF 2.66 x 10(-9) m2/s and for white and grey matter 0.69 x 10(-9) m2/s and 0.87 x 10(-9) m2/s, respectively. CONCLUSION: Velocity-compensating gradients in combination with a high gradient strength were shown to be useful for in vivo diffusion MR imaging.

Keywords

  • Radiology, Nuclear Medicine and Medical Imaging

Other

Published
  • ISSN: 1600-0455
Freddy Ståhlberg
E-mail: freddy.stahlberg [at] med.lu.se

Professor

Medical Radiation Physics, Lund

+46 46 17 31 19

+46 70 688 31 19

32

Professor

Diagnostic Radiology, (Lund)

+46 46 17 70 30

32