Dynamic susceptibility contrast MRI with a prebolus contrast agent administration design for improved absolute quantification of perfusion.
- Medical Radiation Physics, Lund
- Department of Clinical Physiology (Lund)
- Neurology, Lund
- Diagnostic Radiology, (Lund)
Publishing year: 2014
Publication/Series: Magnetic Resonance in Medicine
Document type: Journal article
Publisher: Wiley Online Library
Arterial partial-volume effects (PVEs) often hamper reproducible absolute quantification of cerebral blood flow (CBF) and cerebral blood volume (CBV) obtained by dynamic susceptibility contrast MRI (DSC-MRI). The aim of this study was to examine whether arterial PVEs in DSC-MRI data can be minimized by rescaling the arterial input function (AIF) using a sagittal-sinus venous output function obtained following a prebolus administration of a low dose of contrast agent.
- Radiology, Nuclear Medicine and Medical Imaging
- ISSN: 1522-2594