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Carl Borrebaeck

Carl Borrebaeck

Professor

Carl Borrebaeck

Attovial-based antibody nanoarrays.

Author

  • Peter Ellmark
  • Sara Ghatnekar-Nilsson
  • André Meister
  • Harry Heinzelmann
  • Lars Montelius
  • Christer Wingren
  • Carl Borrebaeck

Summary, in English

Antibody array-based technology is a powerful emerging tool in proteomics, but to enable global proteome analysis, antibody array layouts with even higher density has to be developed. To this end, we have further developed the first generation of a nanoarray platform, based on attoliter sized vials, attovials, which we have characterized and used for the detection of complement factor C1q in human serum samples. Finally, we demonstrated proof-of-concept for individual functionalisation of the attovials with a recombinant antibody.

Department/s

  • Department of Immunotechnology
  • Solid State Physics

Publishing year

2009

Language

English

Pages

5406-5413

Publication/Series

Proteomics

Volume

9

Issue

24

Document type

Journal article

Publisher

John Wiley & Sons Inc.

Topic

  • Immunology in the medical area
  • Condensed Matter Physics

Status

Published

ISBN/ISSN/Other

  • ISSN: 1615-9861