Carl Borrebaeck
Professor
High-throughput proteomics using antibody microarrays
Author
Summary, in English
Antibody-based microarrays are a novel technology that hold great promise in proteomics. Microarrays can be printed with thousands of recombinant antibodies carrying the desired specificities, the biologic sample (e.g., an entire proteome) and any specifically bound analytes detected. The microarray patterns that are generated can then be converted into proteomic maps, or molecular fingerprints, revealing the composition of the proteome. Using this tool, global proteome analysis and protein expression profiling will thus provide new opportunities for biomarker discovery, drug target identification and disease diagnostics, as well as providing insights into disease biology. Intense work is currently underway to develop this novel technology platform into the high-throughput proteomic tool required by the research community.
Department/s
- Department of Immunotechnology
Publishing year
2004
Language
English
Pages
355-364
Publication/Series
Espert Review of Proteomics
Volume
1
Issue
3
Document type
Journal article review
Publisher
Future Drugs Ltd
Topic
- Immunology in the medical area
Status
Published
ISBN/ISSN/Other
- ISSN: 1744-8387