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Germline rearrangements in families with strong family history of glioma and malignant melanoma, colon, and breast cancer.

Author:
  • Ulrika Andersson
  • Carl Wibom
  • Kristina Cederquist
  • Steina Aradottir
  • Åke Borg
  • Georgina N Armstrong
  • Sanjay Shete
  • Ching C Lau
  • Matthew N Bainbridge
  • Elizabeth B Claus
  • Jill Barnholtz-Sloan
  • Rose Lai
  • Dora Il'yasova
  • Richard S Houlston
  • Joellen Schildkraut
  • Jonine L Bernstein
  • Sara H Olson
  • Robert B Jenkins
  • Daniel H Lachance
  • Margaret Wrensch
  • Faith G Davis
  • Ryan Merrell
  • Christoffer Johansen
  • Siegal Sadetzki
  • Melissa L Bondy
  • Beatrice S Melin
Publishing year: 2014
Language: English
Pages: 1333-1340
Publication/Series: Neuro-Oncology
Volume: 16
Issue: 10
Document type: Journal article
Publisher: Oxford University Press

Abstract english

Although familial susceptibility to glioma is known, the genetic basis for this susceptibility remains unidentified in the majority of glioma-specific families. An alternative approach to identifying such genes is to examine cancer pedigrees, which include glioma as one of several cancer phenotypes, to determine whether common chromosomal modifications might account for the familial aggregation of glioma and other cancers.

Keywords

  • Cancer and Oncology

Other

Published
  • ISSN: 1523-5866
Åke Borg
Åke Borg
E-mail: ake.borg [at] med.lu.se

Principal investigator

Oncology and Pathology, MV

+46 46 275 25 52

MV 404 C21B2

90

Project manager

Familial Breast Cancer

90

Professor

Oncology and Pathology, MV

MV 404 C21C2

90