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Higher occurrence of childhood cancer in families with germline mutations in BRCA2, MMR and CDKN2A genes.

Author:
  • Susanne Magnusson
  • Åke Borg
  • Ulf Kristoffersson
  • Mef Nilbert
  • Thomas Wiebe
  • Håkan Olsson
Publishing year: 2008
Language: English
Pages: 331-337
Publication/Series: Familial Cancer
Volume: 7
Document type: Journal article
Publisher: Kluwer

Abstract english

The contribution of hereditary factors for development of childhood tumors is limited to some few known syndromes associated with predominance of tumors in childhood. Occurrence of childhood tumors in hereditary cancer syndromes such as BRCA1/2 associated breast and ovarian cancer, DNA-mismatch repair (MMR) genes associated hereditary non polyposis colorectal cancer and CDKN2A associated familial malignant melanoma are very little studied. Herein we report the prevalence of childhood tumors (diagnosed

Keywords

  • Cancer and Oncology

Other

Published
  • ISSN: 1389-9600
Åke Borg
Åke Borg
E-mail: ake.borg [at] med.lu.se

Principal investigator

Oncology and Pathology, MV

+46 46 275 25 52

MV 404 C21B2

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Project manager

Familial Breast Cancer

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Professor

Oncology and Pathology, MV

MV 404 C21C2

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