International network of cancer genome projects

Summary, in English

The International Cancer Genome Consortium (ICGC) was launched to coordinate large-scale cancer genome studies in tumours from 50 different cancer types and/or subtypes that are of clinical and societal importance across the globe. Systematic studies of more than 25,000 cancer genomes at the genomic, epigenomic and transcriptomic levels will reveal the repertoire of oncogenic mutations, uncover traces of the mutagenic influences, define clinically relevant subtypes for prognosis and therapeutic management, and enable the development of new cancer therapies.

• Author: Thomas J. Hudson; Warwick Anderson; Axel Aretz; Anna D. Barker; Cindy Bell; Rosa R. Bernabe; M. K. Bhan; Fabien Calvo; Iiro Eerola; Daniela S. Gerhard; Alan Guttmacher; Mark Guyer; Fiona M. Hemsley; Jennifer L. Jennings; David Kerr; Peter Klatt; Patrik Kolar; Jun Kusuda; David P. Lane; Frank Laplace; Youyong Lu; Gerd Nettekoven; Brad Ozenberger; Jane Peterson; T. S. Rao; Jacques Remacle; Alan J. Schafer; Tatsuhiro Shibata; Michael R. Stratton; Joseph G. Vockley; Koichi Watanabe; Huanming Yang; Matthew M. F. Yuen; M. Knoppers; Martin Bobrow; Anne Cambon-Thomsen; Lynn G. Dressler; Stephanie O. M. Dyke; Yann Joly; Kazuto Kato; Karen L. Kennedy; Pilar Nicolas; Michael J. Parker; Emmanuelle Rial-Sebbag; Carlos M. Romeo-Casabona; Kenna M. Shaw; Susan Wallace; Georgia L. Wiesner; Nikolajs Zeps; Peter Lichter; Andrew V. Biankin; Christian Chabannon; Lynda Chin; Bruno Clement; Enrique de Alava; Francoise Degos; Martin L. Ferguson; Peter Geary; D. Neil Hayes; Amber L. Johns; Hidewaki Nakagawa; Robert Penny; Miguel A. Piris; Rajiv Sarin; Aldo Scarpa; Tatsuhiro Shibata; Marc van de Vijver; P. Andrew Futreal; Hiroyuki Aburatani; Monica Bayes; David D. L. Bowtell; Peter J. Campbell; Xavier Estivill; Sean M. Grimmond; Ivo Gut; Martin Hirst; Carlos Lopez-Otin; Partha Majumder; Marco Marra; Hidewaki Nakagawa; Zemin Ning; Xose S. Puente; Yijun Ruan; Tatsuhiro Shibata; Michael R. Stratton; Hendrik G. Stunnenberg; Harold Swerdlow; Victor E. Velculescu; Richard K. Wilson; Hong H. Xue; Liu Yang; Paul T. Spellman; Gary D. Bader; Paul C. Boutros; Peter J. Campbell; Paul Flicek; Gad Getz; Roderic Guigo; Guangwu Guo; David Haussler; Simon Heath; Tim J. Hubbard; Tao Jiang; Steven M. Jones; Qibin Li; Nuria Lopez-Bigas; Ruibang Luo; John V. Pearson; Xose S. Puente; Victor Quesada; Benjamin J. Raphael; Chris Sander; Tatsuhiro Shibata; Terence P. Speed; Joshua M. Stuart; Jon W. Teague; Yasushi Totoki; Tatsuhiko Tsunoda; Alfonso Valencia; David A. Wheeler; Honglong Wu; Shancen Zhao; Guangyu Zhou; Lincoln D. Stein; Roderic Guigo; Tim J. Hubbard; Yann Joly; Steven M. Jones; Mark Lathrop; Nuria Lopez-Bigas; B. F. Francis Ouellette; Paul T. Spellman; Jon W. Teague; Gilles Thomas; Alfonso Valencia; Teruhiko Yoshida; Karen L. Kennedy; Myles Axton; Stephanie O. M. Dyke; P. Andrew Futreal; Chris Gunter; Mark Guyer; John D. McPherson; Linda J. Miller; Brad Ozenberger; Arek Kasprzyk; Junjun Zhang; Syed A. Haider; Jianxin Wang; Christina K. Yung; Anthony Cross; Yong Liang; Saravanamuttu Gnaneshan; Jonathan Guberman; Jack Hsu; Martin Bobrow; Don R. C. Chalmers; Karl W. Hasel; Yann Joly; Terry S. H. Kaan; Karen L. Kennedy; Bartha M. Knoppers; William W. Lowrance; Tohru Masui; Pilar Nicolas; Emmanuelle Rial-Sebbag; Laura Lyman Rodriguez; Catherine Vergely; Teruhiko Yoshida; Sean M. Grimmond; Andrew V. Biankin; David D. L. Bowtell; Nicole Cloonan; Anna Defazio; James R. Eshleman; Dariush Etemadmoghadam; Brooke A. Gardiner; James G. Kench; Aldo Scarpa; Robert L. Sutherland; Margaret A. Tempero; Nicola J. Waddell; Peter J. Wilson; Steve Gallinger; Ming-Sound Tsao; Patricia A. Shaw; Gloria M. Petersen; Debabrata Mukhopadhyay; Lynda Chin; Ronald A. DePinho; Sarah Thayer; Lakshmi Muthuswamy; Kamran Shazand; Timothy Beck; Michelle Sam; Lee Timms; Vanessa Ballin; Youyong Lu; Jiafu Ji; Xiuqing Zhang; Feng Chen; Xueda Hu; Guangyu Zhou; Qi Yang; Geng Tian; Lianhai Zhang; Xiaofang Xing; Xianghong Li; Zhenggang Zhu; Yingyan Yu; Jun Yu; Huanming Yang; Mark Lathrop; Joerg Tost; Paul Brennan; Ivana Holcatova; David Zaridze; Alvis Brazma; Lars Egevad; Egor Prokhortchouk; Rosamonde Elizabeth Banks; Mathias Uhlen; Anne Cambon-Thomsen; Juris Viksna; Fredrik Ponten; Konstantin Skryabin; Michael R. Stratton; P. Andrew Futreal; Ewan Birney; Åke Borg; Anne-Lise Borresen-Dale; Carlos Caldas; John A. Foekens; Sancha Martin; Jorge S. Reis-Filho; Andrea L. Richardson; Christos Sotiriou; Hendrik G. Stunnenberg; Gilles Thomas; Marc van de Vijver; Laura van't Veer; Daniel Birnbaum; Helene Blanche; Pascal Boucher; Sandrine Boyault; Christian Chabannon; Ivo Gut; Jocelyne D. Masson-Jacquemier; Mark Lathrop; Iris Pauporte; Xavier Pivot; Anne Vincent-Salomon; Eric Tabone; Charles Theillet; Gilles Thomas; Joerg Tost; Isabelle Treilleux; Paulette Bioulac-Sage; Bruno Clement; Thomas Decaens; Francoise Degos; Dominique Franco; Ivo Gut; Marta Gut; Simon Heath; Mark Lathrop; Didier Samuel; Gilles Thomas; Jessica Zucman-Rossi; Peter Lichter; Roland Eils; Benedikt Brors; Jan O. Korbel; Andrey Korshunov; Pablo Landgraf; Hans Lehrach; Stefan Pfister; Bernhard Radlwimmer; Guido Reifenberger; Michael D. Taylor; Christof von Kalle; Partha P. Majumder; Rajiv Sarin; Aldo Scarpa; Paolo Pederzoli; Rita T. Lawlor; Massimo Delledonne; Alberto Bardelli; Andrew V. Biankin; Sean M. Grimmond; Thomas Gress; David Klimstra; Giuseppe Zamboni; Tatsuhiro Shibata; Yusuke Nakamura; Hidewaki Nakagawa; Jun Kusuda; Tatsuhiko Tsunoda; Satoru Miyano; Hiroyuki Aburatani; Kazuto Kato; Akihiro Fujimoto; Teruhiko Yoshida; Elias Campo; Carlos Lopez-Otin; Xavier Estivill; Roderic Guigo; Silvia de Sanjose; Miguel A. Piris; Emili Montserrat; Marcos Gonzalez-Diaz; Xose S. Puente; Pedro Jares; Alfonso Valencia; Heinz Himmelbaue; Victor Quesada; Silvia Bea; Michael R. Stratton; P. Andrew Futreal; Peter J. Campbell; Anne Vincent-Salomon; Andrea L. Richardson; Jorge S. Reis-Filho; Marc van de Vijver; Gilles Thomas; Jocelyne D. Masson-Jacquemier; Samuel Aparicio; Ake Borg; Anne-Lise Borresen-Dale; Carlos Caldas; John A. Foekens; Hendrik G. Stunnenberg; Laura van't Veer; Douglas F. Easton; Paul T. Spellman; Sancha Martin; Lynda Chin; Francis S. Collins; Carolyn C. Compton; Martin L. Ferguson; Gad Getz; Chris Gunter; Mark Guyer; D. Neil Hayes; Eric S. Lander; Brad Ozenberger; Robert Penny; Jane Peterson; Chris Sander; Terence P. Speed; Paul T. Spellman; David A. Wheeler; Richard K. Wilson; Lynda Chin; Bartha M. Knoppers; Eric S. Lander; Peter Lichter; Michael R. Stratton; Martin Bobrow; Wylie Burke; Francis S. Collins; Ronald A. DePinho; Douglas F. Easton; P. Andrew Futreal; Anthony R. Green; Mark Guyer; Stanley R. Hamilton; Tim J. Hubbard; Olli P. Kallioniemi; Karen L. Kennedy; Timothy J. Ley; Edison T. Liu; Youyong Lu; Partha Majumder; Marco Marra; Brad Ozenberger; Jane Peterson; Alan J. Schafer; Paul T. Spellman; Hendrik G. Stunnenberg; Brandon J. Wainwright; Richard K. Wilson; Huanming Yang
• Department/s: Breastcancer-genetics; BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
• Publishing year: 2010
• Language: English
• Pages: 993-998
• Publication/Series: Nature
• Volume: 464
• Issue: 7291
• Links: http://dx.doi.org/10.1038/nature08987
• Document type: Journal article
• Publisher: Nature Publishing Group
• Topic: Cancer and Oncology
• Status: Published
• ISBN/ISSN/Other: ISSN: 0028-0836