Åke Borg
Principal investigator
High risk of tobacco-related cancers in CDKN2A mutation-positive melanoma families.
Author
Summary, in English
Germline mutations in the tumour suppressor gene CDKN2A occur in 5-20% of familial melanoma cases. A single founder mutation, p.Arg112dup, accounts for the majority of CDKN2A mutations in Swedish carriers. In a national program, carriers of p.Arg112dup mutation have been identified. The aim of this study was to assess cancer risks in p.Arg112dup carriers and their first degree relatives (FDRs) and second degree relatives (SDRs).
Department/s
- Breastcancer-genetics
- BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
- Surgery (Lund)
- EpiHealth: Epidemiology for Health
Publishing year
2014
Language
English
Pages
545-552
Publication/Series
Journal of Medical Genetics
Volume
51
Issue
8
Links
Document type
Journal article
Publisher
BMJ Publishing Group
Topic
- Medical Genetics
Status
Published
ISBN/ISSN/Other
- ISSN: 0022-2593